Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25306765 | 0.89 | ALDH1A1 (0.43) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL23623916 | 0.84 | HDAC8 (0.40) | ALDH1A1TP53SCN1ASCN2ASCN3A | |
| SCHEMBL23157115 | 0.83 | TP53 (0.42) | ALDH1A1TP53SCN1ASCN2ASCN3A | |
| SCHEMBL15083519 | 0.83 | CA1 (0.42) | TP53SCN1ASCN2ASCN3ACA2 | |
| SCHEMBL16674090 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TP53SCN1ASCN2ASCN3A | |
| SCHEMBL23623815 | 0.82 | TP53 (0.36) | ALDH1A1TP53SCN1ASCN2ASCN3A | |
| SCHEMBL21671191 | 0.81 | TP53 (0.38) | TP53SCN1ASCN2ASCN3ACA2 | |
| SCHEMBL132773 | 0.80 | ALDH1A1 (0.78) | ALDH1A1CYP3A4CA2SLC6A3MEN1 | |
| SCHEMBL23623804 | 0.79 | HDAC8 (0.41) | ALDH1A1TP53SCN1ASCN2ASCN3A | |
| SCHEMBL12879091 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP3A4TP53CA2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241507-B2 | Near-infrared chemiluminescent probes for in-vivo imaging | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-02-08 | — | — | US | disclosed |
| US-20210207188-A1 | BETA-LACTAM COMPOUNDS AND METHODS OF USE THEREOF | THE UNIVERSITY OF HONG KONG (HK) | 2021-07-08 | — | — | US | disclosed |
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-03-04 | — | — | US | disclosed |
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |
| US-9409952-B2 | Peptide-compound cyclization method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-08-09 | — | — | US | disclosed |
| US-20150080549-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-03-19 | — | — | US | disclosed |
| US-20150080549-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-03-19 | — | — | US | disclosed |
| US-8518891-B2 | Chemotherapeutic conjugates and methods of use | HU LONGQIN (US) | 2013-08-27 | — | — | US | disclosed |
| US-20100075927-A1 | CHEMOTHERAPEUTIC CONJUGATES AND METHODS OF USE | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-03-25 | — | — | US | disclosed |
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | FRUTAROM LTD. (IL) | 2008-09-11 | — | — | US | disclosed |
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | FRUTAROM LTD. (IL) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075927-A1 | CHEMOTHERAPEUTIC CONJUGATES AND METHODS OF USE | DNPEP, ANPEP, ENPEP | ALDH1A1 2003/4885CYP3A4 2842/4885TP53 107/4885 |
| US-20210207188-A1 | BETA-LACTAM COMPOUNDS AND METHODS OF USE THEREOF | MGAM, SI, PGLS | ALDH1A1 1532/4885CYP3A4 318/4885TP53 4680/4885 |
| US-20210061860-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | ALDH1A1 4857/4885CYP3A4 4383/4885TP53 2654/4885 |
| US-11241507-B2 | Near-infrared chemiluminescent probes for in-vivo imaging | DHPS, DOHH, DAZAP1 | ALDH1A1 486/4885CYP3A4 343/4885TP53 2764/4885 |
| US-20080221303-A1 | Method for the Preparation of Peptide-Oligonucleotide Conjugates | VIP, PTMS, SSTR4 | ALDH1A1 4552/4885CYP3A4 3770/4885TP53 1803/4885 |
| US-20150080549-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | VIP, NGLY1, GLP1R | ALDH1A1 4857/4885CYP3A4 4383/4885TP53 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.