Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945848 | 0.78 | GBA1 (0.44) | GLSGBA1 | |
| SCHEMBL16674423 | 0.76 | GBA1 (0.45) | GBA1ANPEP | |
| SCHEMBL22861720 | 0.75 | GBA1 (0.44) | GBA1ANPEP | |
| SCHEMBL16674336 | 0.73 | CYP1A2 (0.43) | — | |
| SCHEMBL21992355 | 0.69 | MAPT (0.39) | GLSGBA1 | |
| SCHEMBL17704734 | 0.69 | LMNA (0.38) | — | |
| SCHEMBL19535087 | 0.68 | ALDH1A1 (0.56) | — | |
| SCHEMBL23696408 | 0.68 | ADRB2 (0.40) | GLSGBA1 | |
| SCHEMBL24812463 | 0.67 | GBA1 (0.53) | GLSGBA1 | |
| SCHEMBL18623460 | 0.67 | L3MBTL1 (0.44) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9730976-B2 | Homo- and heterodimeric SMAC mimetic compounds as apoptosis inducers | BIONTECH AG (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20160317605-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | BIONTECH AG (DE) | 2016-11-03 | — | — | US | disclosed |
| US-9321808-B2 | Homo- and heterodimeric SMAC mimetic compounds as apoptosis inducers | BIONTECH AG (DE) | 2016-04-26 | — | — | US | disclosed |
| US-20150119342-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160317605-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | BID, BIRC2, API5 | GLS 2643/4885GBA1 4164/4885ANPEP 3087/4885 |
| US-20150119342-A1 | New Homo- and Heterodimeric SMAC Mimetic Compounds as Apoptosis Inducers | BID, BIRC2, API5 | GLS 2643/4885GBA1 4164/4885ANPEP 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.