Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667518 | 1.00 | KIF11 (0.39) | KIF11TRPM8SIGMAR1DRD2HTR2A | |
| SCHEMBL2904993 | 0.84 | TRPM8 (0.40) | KIF11TRPM8SIGMAR1DRD2HTR2A | |
| SCHEMBL2904991 | 0.84 | TRPM8 (0.40) | KIF11TRPM8SIGMAR1DRD2HTR2A | |
| SCHEMBL4551228 | 0.79 | TRPM8 (0.46) | TRPM8SIGMAR1DRD2HTR2AEPHX2 | |
| SCHEMBL4183035 | 0.74 | KIF11 (0.36) | KIF11FNTAFNTBSCD | |
| SCHEMBL4183030 | 0.74 | KIF11 (0.36) | KIF11FNTAFNTBSCD | |
| SCHEMBL29194054 | 0.70 | OPRL1 (0.40) | TRPM8SIGMAR1 | |
| SCHEMBL17476110 | 0.65 | TRPM8 (0.41) | TRPM8SIGMAR1DRD2HTR2AEPHX2 | |
| SCHEMBL8410197 | 0.65 | TRPM8 (0.49) | TRPM8SIGMAR1DRD2HTR2AEPHX2 | |
| SCHEMBL1246125 | 0.65 | SIGMAR1 (0.44) | TRPM8SIGMAR1DRD2HTR2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886653-B1 | PROKARYOTIC BACTERIUM PHOTOINDUCED GENE EXPRESSION SYSTEM AND METHOD FOR REGULATING AND CONTROLLING GENE EXPRESSION BY USING SAME | UNIV EAST CHINA SCIENCE & TECH (CN) | 2020-10-21 | — | — | EP | disclosed |
| US-10184126-B2 | Light-switchable gene expression system and the methods for controlling gene expression in prokaryotic bacterium | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-01-22 | — | — | US | disclosed |
| EP-3426783-A1 | ULTRASOUND METHOD | Institute of Science and Technology Austria (AT) | 2019-01-16 | — | — | EP | disclosed |
| EP-2682469-B1 | LIGHT-SWITCHABLE GENE EXPRESSION SYSTEM | UNIV EAST CHINA SCIENCE & TECH (CN) | 2018-12-26 | — | — | EP | disclosed |
| US-9839698-B2 | Light-switchable gene expression system | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2017-12-12 | — | — | US | disclosed |
| WO-2017153595-A1 | ULTRASOUND METHOD | INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA (IST AUSTRIA) (AT) | 2017-09-14 | — | — | WO | disclosed |
| US-20160040173-A1 | Light-Switchable Gene Expression System and the Methods for Controlling Gene Expression in Prokaryotic Bacterium | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-02-11 | — | — | US | disclosed |
| US-9097703-B2 | Light controlled protein dimerization in cells | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| EP-2886653-A1 | PROKARYOTIC BACTERIUM PHOTOINDUCED GENE EXPRESSION SYSTEM AND METHOD FOR REGULATING AND CONTROLLING GENE EXPRESSION BY USING SAME | East China University Of Science And Technology (CN) | 2015-06-24 | — | — | EP | disclosed |
| EP-2682469-A1 | OPTICALLY CONTROLLED GENE EXPRESSION SYSTEM | East China University Of Science And Technology (CN) | 2014-01-08 | — | — | EP | disclosed |
| US-20130345294-A1 | Light-Switchable Gene Expression System | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-12-26 | — | — | US | disclosed |
| US-20120237966-A1 | Light Controlled Protein Dimerization in Cells | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2012-09-20 | — | — | US | disclosed |
| WO-2011041327-A1 | LIGHT CONTROLLED PROTEIN DIMERIZATION IN CELLS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-04-07 | — | — | WO | disclosed |