Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904993 | 0.82 | TRPM8 (0.40) | TRPM8EPHX2EPHX1SIGMAR1HDAC9 | |
| SCHEMBL2904991 | 0.82 | TRPM8 (0.40) | TRPM8EPHX2EPHX1SIGMAR1HDAC9 | |
| SCHEMBL29194054 | 0.81 | OPRL1 (0.40) | TRPM8SIGMAR1HDAC9HCAR2 | |
| SCHEMBL1667521 | 0.79 | KIF11 (0.39) | TRPM8EPHX2EPHX1SIGMAR1DRD2 | |
| SCHEMBL1667518 | 0.79 | KIF11 (0.39) | TRPM8EPHX2EPHX1SIGMAR1DRD2 | |
| SCHEMBL8410197 | 0.78 | TRPM8 (0.49) | TRPM8EPHX2EPHX1SIGMAR1HDAC9 | |
| SCHEMBL15882569 | 0.77 | TRPM8 (0.48) | TRPM8EPHX2EPHX1SIGMAR1HDAC9 | |
| SCHEMBL2283973 | 0.77 | TRPM8 (0.48) | TRPM8EPHX2EPHX1SIGMAR1HDAC9 | |
| SCHEMBL3519974 | 0.75 | TRPM8 (0.47) | TRPM8SIGMAR1PPARGPPARA | |
| SCHEMBL29455981 | 0.75 | TRPM8 (0.47) | TRPM8SIGMAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098245-B2 | Polynucleotide cleavage agent switched on by photo irradiation | TOTTORI UNIVERSITY (JP) | 2006-08-29 | — | — | US | claimed |
| US-20040058346-A1 | Polynucleotide cleavage agent switched on by photo irradiation | TOTTORI UNIVERSITY (JP) | 2004-03-25 | — | — | US | claimed |
| CN-114728970-A | Optical proximity analysis of protein-protein interactions in cells | 芝加哥大学 | 2022-07-08 | — | — | CN | disclosed |
| US-7514404-B2 | PNA-neamine conjugates and methods for producing and using the same | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070225239-A1 | Pna-Neamine Conjugates and Methods for Producing and Using the Same | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-09-27 | — | — | US | disclosed |
| US-7098245-B2 | Polynucleotide cleavage agent switched on by photo irradiation | TOTTORI UNIVERSITY (JP) | 2006-08-29 | — | — | US | disclosed |
| WO-2005060573-A2 | PNA-NEAMINE CONJUGATES AND METHODS FOR PRODUCING AND USING THE SAME | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20040058346-A1 | Polynucleotide cleavage agent switched on by photo irradiation | TOTTORI UNIVERSITY (JP) | 2004-03-25 | — | — | US | disclosed |
| CN-1230955-A | Dihydrobenzopyrans and related compounds as anti-inflammatory agents | PROCTER & GAMBLE (US) | 1999-10-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058346-A1 | Polynucleotide cleavage agent switched on by photo irradiation | NSUN2, CPSF1, POLL | TRPM8 2600/4885EPHX2 1594/4885EPHX1 3500/4885 |
| US-20070225239-A1 | Pna-Neamine Conjugates and Methods for Producing and Using the Same | NCL, PNMT, RNMT | TRPM8 4769/4885EPHX2 1513/4885EPHX1 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.