Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 6/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904991 | 1.00 | TRPM8 (0.40) | TRPM8KIF11SIGMAR1EPHX2EPHX1 | |
| SCHEMBL1667521 | 0.84 | KIF11 (0.39) | TRPM8KIF11SIGMAR1EPHX2EPHX1 | |
| SCHEMBL1667518 | 0.84 | KIF11 (0.39) | TRPM8KIF11SIGMAR1EPHX2EPHX1 | |
| SCHEMBL4551228 | 0.82 | TRPM8 (0.46) | TRPM8SIGMAR1EPHX2EPHX1HDAC9 | |
| SCHEMBL29194054 | 0.73 | OPRL1 (0.40) | TRPM8SIGMAR1HDAC9ALDH1A1HCAR2 | |
| SCHEMBL3218026 | 0.70 | TRPM8 (0.43) | TRPM8SIGMAR1EPHX2EPHX1HDAC9 | |
| SCHEMBL3519974 | 0.68 | TRPM8 (0.47) | TRPM8SIGMAR1PPARGPPARA | |
| Methyl Alcohol SCHEMBL28796336 | 0.68 | SIGMAR1 (0.42) | TRPM8SIGMAR1EPHX2EPHX1HDAC9 | |
| SCHEMBL29455981 | 0.68 | TRPM8 (0.47) | TRPM8SIGMAR1PPARGPPARA | |
| SCHEMBL17476110 | 0.68 | TRPM8 (0.41) | TRPM8SIGMAR1EPHX2EPHX1HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790733-B1 | SCREENING METHOD AND SCREENING APPARATUS USING MICRO-CHAMBER ARRAY | SUNTORY HOLDINGS LTD (JP) | 2010-08-04 | — | — | EP | disclosed |
| US-20070269794-A1 | Screening Method and Screening Apparatus Using Micro-Chamber Array | SUNTORY HOLDINGS LIMITED (JP) | 2007-11-22 | — | — | US | disclosed |
| CN-101014718-A | Screening method using microchamber array and screening apparatus | SUNTORY LTD (JP) | 2007-08-08 | — | — | CN | disclosed |
| EP-1790733-A1 | SCREENING METHOD AND SCREENING APPARATUS USING MICRO-CHAMBER ARRAY | SUNTORY LIMITED (JP) | 2007-05-30 | — | — | EP | disclosed |