SCHEMBL16675484

SCHEMBL16675484

COc1cc(-c2nnc(SCC(=O)Nc3ccc(Oc4ccccc4)cc3)n2N)cc(OC)c1OC

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TUBB4A P04350 1/20 0.80
▸ TUBB P07437 1/20 0.80
▸ TUBA3C P0DPH7 1/20 0.80
▸ TUBA1B P68363 1/20 0.80
▸ TUBA4A P68366 1/20 0.80
▸ TUBB4B P68371 1/20 0.80
▸ TUBB3 Q13509 1/20 0.80
▸ TUBB2A Q13885 1/20 0.80
▸ TUBB8 Q3ZCM7 1/20 0.80
▸ TUBA3E Q6PEY2 1/20 0.80
▸ TUBA1A Q71U36 1/20 0.80
▸ TUBA1C Q9BQE3 1/20 0.80
▸ TUBB6 Q9BUF5 1/20 0.80
▸ TUBB2B Q9BVA1 1/20 0.80
▸ TUBB1 Q9H4B7 1/20 0.80
▸ MAPT P10636 4/20 0.72
▸ ALOX15 P16050 2/20 0.72
▸ GLA P06280 2/20 0.68
▸ TSHR P16473 3/20 0.64
▸ POLB P06746 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1906927 0.76 TUBB4A (0.59) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL27173136 0.74 TUBB4A (0.73) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15986354 0.73 LMNA (0.92) MAPTALOX15POLBALDH1A1HSD17B10
SCHEMBL4204658 0.72 MEN1 (0.64) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15986565 0.72 MAPT (0.82) MAPTALOX15POLBKDM4CALDH1A1
SCHEMBL13831532 0.71 MAPT (0.65) MAPTTSHRALDH1A1GAALMNA
SCHEMBL25482057 0.70 CA2 (0.66) MAPTALOX15TSHRPOLBALDH1A1
SCHEMBL4204267 0.69 ALDH1A1 (0.69) MAPTALOX15TSHRPOLBALDH1A1
SCHEMBL20042589 0.69 MAPT (0.66) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL20067958 0.69 LMNA (0.80) MAPTGLAALDH1A1HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737462-B2 Methods for modulating plant response to environmentally-induced stress HOWARD UNIVERSITY (US) 2023-08-29 — — US disclosed
US-11737462-B2 Methods for modulating plant response to environmentally-induced stress HOWARD UNIVERSITY (US) 2023-08-29 — — US disclosed
US-20150119250-A1 METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS GEORGETOWN UNIVERSITY 2015-04-30 — — US disclosed
US-20150119250-A1 METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS GEORGETOWN UNIVERSITY 2015-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737462-B2 Methods for modulating plant response to environmentally-induced stress RACK1, ROS1, HSF1 TUBB4A 851/4885TUBB 794/4885TUBA3C 1110/4885
US-20150119250-A1 METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS RACK1, ROS1, HSF1 TUBB4A 851/4885TUBB 794/4885TUBA3C 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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