Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668131 | 0.83 | ELANE (0.55) | ELANEESRRAESR2 | |
| SCHEMBL30201783 | 0.83 | ELANE (0.54) | ELANE | |
| SCHEMBL1670142 | 0.83 | ELANE (0.44) | ALDH1A1MAPTELANEL3MBTL1 | |
| SCHEMBL12670691 | 0.78 | RORC (0.57) | ELANE | |
| SCHEMBL1078113 | 0.78 | L3MBTL1 (0.53) | MAPTL3MBTL1LMNATP53ESRRA | |
| SCHEMBL12670692 | 0.77 | ELANE (0.54) | MAPTELANE | |
| SCHEMBL16517760 | 0.74 | PDE4A (0.56) | ELANE | |
| SCHEMBL1667649 | 0.74 | L3MBTL1 (0.49) | ALDH1A1MAPTELANEL3MBTL1ESRRA | |
| SCHEMBL7170779 | 0.73 | PDE4A (0.60) | ALDH1A1MAPTLMNATP53KAT2B | |
| SCHEMBL10095240 | 0.72 | L3MBTL1 (0.53) | L3MBTL1ESRRAESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |