Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667607 | 0.83 | ALDH1A1 (0.52) | ELANEALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1668131 | 0.78 | ELANE (0.55) | ELANE | |
| SCHEMBL30201783 | 0.77 | ELANE (0.54) | ELANEPDE4AKCNH2 | |
| SCHEMBL1668155 | 0.76 | USP14 (0.33) | ELANEALDH1A1MAPT | |
| SCHEMBL12670691 | 0.72 | RORC (0.57) | ELANE | |
| SCHEMBL12670692 | 0.71 | ELANE (0.54) | ELANEMAPT | |
| SCHEMBL16517760 | 0.71 | PDE4A (0.56) | ELANEPDE4AKCNH2 | |
| SCHEMBL7844045 | 0.69 | ELANE (0.57) | ELANE | |
| SCHEMBL15559787 | 0.68 | ELANE (0.52) | ELANE | |
| SCHEMBL8513964 | 0.67 | ELANE (0.51) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |