Sugi Predict

Sugi Predict / Compounds / SCHEMBL166766

SCHEMBL166766

SCHEMBL166766

Cc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.53
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ POLB P06746 2/20 0.50
▸ PLAU P00749 1/20 0.50
▸ MAPK1 P28482 1/20 0.47
▸ HTT P42858 2/20 0.47
▸ GAA P10253 1/20 0.47
▸ KMT2A Q03164 4/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ NPC1 O15118 2/20 0.47
▸ RAB9A P51151 2/20 0.47
▸ PKM P14618 1/20 0.47
▸ L3MBTL1 Q9Y468 3/20 0.46
▸ LMNA P02545 2/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ STAT3 P40763 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28721633 0.96 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
Acetic Acid SCHEMBL28420283 0.88 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
SCHEMBL21419159 0.86 HTT (0.40) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
SCHEMBL17177781 0.86 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
SCHEMBL12241428 0.81 CHRNB2 (0.40) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
SCHEMBL31018138 0.80 AGBL2 (0.50) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
SCHEMBL2084458 0.80 AGBL2 (0.50) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
SCHEMBL29414916 0.78 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
Ammonia Solution, Strong SCHEMBL28479749 0.78 AGBL2 (0.49) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU
SCHEMBL120994 0.78 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2KDM4EPOLBPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099838-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF FLUOPYRAM BEST AGROLIFE LIMITED (IN) 2026-05-15 — — WO claimed
CN-119143663-A Method for preparing 2-aminomethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride 阜新都创新材料科技有限公司 2024-12-17 — — CN claimed
CN-114230513-B Synthesis method of 3-chloro-2-methyl-5-trifluoromethyl pyridine 大连九信精细化工有限公司 2024-11-29 — — CN claimed
CN-114230513-A Synthetic method of 3-chloro-2-methyl-5-trifluoromethylpyridine 大连九信精细化工有限公司 2022-03-25 — — CN claimed
EP-3363788-A1 CANNABINOID RECEPTOR MODULATORS Arena Pharmaceuticals, Inc. (US) 2018-08-22 — — EP claimed
US-20130165412-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2013-06-27 — — US claimed
US-20120214766-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2012-08-23 — — US claimed
EP-2470508-A1 CANNABINOID RECEPTOR MODULATORS Arena Pharmaceuticals, Inc. (US) 2012-07-04 — — EP claimed
WO-2011025541-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. (US) 2011-03-03 — — WO claimed
EP-1874734-A1 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS Solvay Pharmaceuticals B.V. (NL) 2008-01-09 — — EP claimed
US-20060194779-A1 1H-imidazole derivatives as cannabinoid CB2 receptor modulators ABBVIE B.V. (NL) 2006-08-31 — — US claimed
WO-2006087355-A1 1H-IMIDIAZOLE DERIVATIVES AS CANNABINOID CB2 RECEPTOR MODULATORS SOLVAY PHARMACEUTICALS B.V. (NL) 2006-08-24 — — WO claimed
WO-2026099838-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF FLUOPYRAM BEST AGROLIFE LIMITED (IN) 2026-05-15 — — WO disclosed
CN-120623102-A Environment-friendly preparation method of fluopyram intermediate 3-chloro-5- (trifluoromethyl) -2-ethylamino pyridine 利民化学有限责任公司 2025-09-12 — — CN disclosed
CN-119143663-A Method for preparing 2-aminomethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride 阜新都创新材料科技有限公司 2024-12-17 — — CN disclosed
CN-119143663-A Method for preparing 2-aminomethyl-3-chloro-5-trifluoromethyl pyridine hydrochloride 阜新都创新材料科技有限公司 2024-12-17 — — CN disclosed
EP-1289958-A2 BENZOPHENONES AS INHIBITORS OF IL-1$g(b) AND TNF-$g(a) Leo Pharma A/S (DK) 2003-03-12 — — EP disclosed
US-6432962-B2 Benzophenones as inhibitors of IL-1β and TNF-α LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 2002-08-13 — — US disclosed
US-20020016347-A1 Benzophenones as inhibitors of IL-1beta and TNF-alpha LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 2002-02-07 — — US disclosed
WO-2001090074-A2 BENZOPHENONES AS INHIBITORS OF IL-1β AND TNF-$g(a) LEO PHARMA A/S (DK) 2001-11-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120214766-A1 CANNABINOID RECEPTOR MODULATORS CNR1, CNR2, TRPV1 ALDH1A1 3623/4885SMN1; SMN2 208/4885KDM4E 3533/4885
US-20020016347-A1 Benzophenones as inhibitors of IL-1beta and TNF-alpha IL1B, IL1A, NFKBIA ALDH1A1 205/4885SMN1; SMN2 3343/4885KDM4E 4128/4885
US-20060194779-A1 1H-imidazole derivatives as cannabinoid CB2 receptor modulators CNR1, CNR2, HRH4 ALDH1A1 1715/4885SMN1; SMN2 4448/4885KDM4E 982/4885
US-20130165412-A1 CANNABINOID RECEPTOR MODULATORS CNR1, CNR2, TRPV1 ALDH1A1 3623/4885SMN1; SMN2 208/4885KDM4E 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.