Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP14 | P54578 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 9/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668123 | 0.83 | MAPT (0.44) | KDM4EALDH1A1TSHRPDE4BMEN1 | |
| SCHEMBL1667769 | 0.80 | ELANE (0.39) | KDM4EUSP14FEN1ELANEKDM4D | |
| SCHEMBL1667703 | 0.80 | USP14 (0.41) | KDM4EUSP14FEN1ELANEKDM4D | |
| SCHEMBL1667847 | 0.80 | USP14 (0.46) | KDM4EUSP14FEN1ELANEKCNMA1 | |
| SCHEMBL1667597 | 0.79 | ELANE (0.38) | KDM4EUSP14FEN1ELANEKDM4D | |
| SCHEMBL1667600 | 0.79 | ELANE (0.38) | KDM4EUSP14FEN1ELANEKDM4D | |
| SCHEMBL1667598 | 0.79 | ELANE (0.38) | KDM4EUSP14FEN1ELANEKDM4D | |
| SCHEMBL1668155 | 0.78 | USP14 (0.33) | KDM4EUSP14FEN1ELANEKDM4D | |
| SCHEMBL1075730 | 0.77 | L3MBTL1 (0.44) | KDM4EALDH1A1TSHRMEN1GAA | |
| SCHEMBL1667710 | 0.76 | USP14 (0.39) | KDM4EUSP14ELANEKDM4DPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |