Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667713 | 1.00 | USP14 (0.39) | USP14ELANEKDM4EPDE4BPDE4D | |
| SCHEMBL1667847 | 0.81 | USP14 (0.46) | USP14ELANEKDM4EPDE4BPDE4D | |
| SCHEMBL1667703 | 0.81 | USP14 (0.41) | USP14ELANEKDM4EKDM4D | |
| SCHEMBL1667576 | 0.76 | KDM4E (0.41) | USP14ELANEKDM4EPDE4BKDM4D | |
| SCHEMBL1667769 | 0.74 | ELANE (0.39) | USP14ELANEKDM4EPDE4BPDE4D | |
| SCHEMBL1667600 | 0.74 | ELANE (0.38) | USP14ELANEKDM4EPDE4BPDE4D | |
| SCHEMBL1667597 | 0.74 | ELANE (0.38) | USP14ELANEKDM4EPDE4BPDE4D | |
| SCHEMBL1667598 | 0.74 | ELANE (0.38) | USP14ELANEKDM4EPDE4BPDE4D | |
| SCHEMBL1668109 | 0.71 | BRD4 (0.38) | USP14ELANEKDM4EPDE4BKDM4D | |
| SCHEMBL1667674 | 0.70 | MAPT (0.49) | USP14PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |