Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | UBE2I | P63279 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668123 | 0.85 | MAPT (0.44) | ALDH1A1MAPTTSHRPKMKDM4E | |
| SCHEMBL1667576 | 0.78 | KDM4E (0.41) | USP14KDM4DALDH1A1MAPTTSHR | |
| SCHEMBL1670142 | 0.76 | ELANE (0.44) | ALDH1A1MAPTELANE | |
| SCHEMBL1667674 | 0.67 | MAPT (0.49) | USP14ALDH1A1MAPTPKMMEN1 | |
| SCHEMBL1075635 | 0.65 | MAPT (0.48) | ALDH1A1MAPTTSHRPKMKDM4E | |
| SCHEMBL1067888 | 0.64 | PREP (0.43) | ALDH1A1PREPMAPT | |
| SCHEMBL6763899 | 0.63 | PREP (0.53) | ALDH1A1PREPKDM4EFEN1 | |
| SCHEMBL16127401 | 0.63 | KDM4D (0.43) | KDM4DALDH1A1ELANEKDM4E | |
| SCHEMBL2958718 | 0.63 | PREP (0.33) | PREP | |
| SCHEMBL1667703 | 0.63 | USP14 (0.41) | USP14KDM4DALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |