Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP14 | P54578 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667847 | 0.85 | USP14 (0.46) | USP14KMT2ALMNAKCNMA1MEN1 | |
| SCHEMBL1668123 | 0.81 | MAPT (0.44) | MAPTALDH1A1RAB9AKMT2ADRD2 | |
| SCHEMBL1667703 | 0.71 | USP14 (0.41) | MAPTALDH1A1USP14TP53 | |
| SCHEMBL1667713 | 0.70 | USP14 (0.39) | USP14PDE4B | |
| SCHEMBL1667710 | 0.70 | USP14 (0.39) | USP14PDE4B | |
| SCHEMBL1667607 | 0.69 | ALDH1A1 (0.52) | MAPTALDH1A1DRD2HTR2ASMN1; SMN2 | |
| SCHEMBL1668155 | 0.67 | USP14 (0.33) | MAPTALDH1A1USP14KMT2APKM | |
| SCHEMBL7278394 | 0.66 | LMNA (0.51) | MAPTALDH1A1RAB9AKMT2APKM | |
| SCHEMBL1040354 | 0.66 | MEN1 (0.46) | MAPTALDH1A1USP14KMT2AHTR2A | |
| SCHEMBL1038038 | 0.65 | MEN1 (0.45) | MAPTALDH1A1USP14KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |