Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16684906 | 0.90 | GPR52 (0.33) | ALDH1A1KDM4EHTTHTR2ADRD2 | |
| SCHEMBL16684943 | 0.72 | HPGD (0.41) | POLBALDH1A1KDM4ETSHRHTT | |
| SCHEMBL16691666 | 0.67 | HTR2C (0.59) | ALDH1A1LMNAMAPK1KDM4EHTR2A | |
| SCHEMBL16691502 | 0.67 | HTR2C (0.59) | ALDH1A1LMNAMAPK1KDM4EHTR2A | |
| SCHEMBL16691526 | 0.67 | HTR2C (0.59) | ALDH1A1LMNAMAPK1KDM4EHTR2A | |
| Hydrochloric Acid SCHEMBL16687125 | 0.67 | HTR2C (0.58) | ALDH1A1LMNAMAPK1KDM4EHTR2A | |
| SCHEMBL7105503 | 0.63 | TSHR (0.51) | POLBALDH1A1TSHRHTTMEN1 | |
| SCHEMBL10158103 | 0.62 | HTT (0.68) | POLBALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL18497851 | 0.60 | ALOX5 (0.47) | POLBLMNATSHRHTTMEN1 | |
| SCHEMBL6360854 | 0.60 | LMNA (0.60) | POLBALDH1A1LMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066344-A1 | 5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE | ARENA PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |