Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075230 | 0.86 | HTR2A (0.34) | HTR2CHTR2BHTR2APRKACAPRKACG | |
| SCHEMBL16685269 | 0.73 | NOTUM (0.50) | HTR2CHTR2BHTR2APRKACAPRKACG | |
| SCHEMBL18190820 | 0.71 | SIRT1 (0.39) | — | |
| SCHEMBL17075188 | 0.71 | PRMT3 (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL17075232 | 0.69 | CYP2C19 (0.39) | HTR2CHTR2BHTR2APRKACAPRKACG | |
| SCHEMBL13438553 | 0.68 | SIGMAR1 (0.37) | HTR2C | |
| SCHEMBL7999624 | 0.67 | LIPG (0.37) | — | |
| SCHEMBL8237522 | 0.66 | PRKACA (0.47) | HTR2APRKACAPRKACGPRKACB | |
| SCHEMBL17075169 | 0.66 | PRMT3 (0.35) | HTR2CHTR2BHTR2APRKACAPRKACG | |
| SCHEMBL17075106 | 0.65 | PRMT3 (0.32) | HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066344-A1 | 5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE | ARENA PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |