Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262406 | 1.00 | — | — | |
| SCHEMBL10816126 | 1.00 | — | — | |
| SCHEMBL9019381 | 0.92 | — | — | |
| SCHEMBL9808495 | 0.92 | — | — | |
| SCHEMBL9647565 | 0.82 | LMNA (0.35) | LMNATSHR | |
| SCHEMBL12796396 | 0.78 | LMNA (0.34) | LMNATSHRMET | |
| SCHEMBL12796387 | 0.77 | LMNA (0.33) | LMNATSHRMET | |
| SCHEMBL21119422 | 0.72 | KDM4E (0.31) | — | |
| SCHEMBL12796383 | 0.70 | MET (0.36) | LMNATSHRMET | |
| SCHEMBL12796478 | 0.69 | KMT2A (0.36) | LMNATSHRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4280882-A2 | MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS | JP LABORATORIES, INC. (US) | 2023-11-29 | — | — | EP | claimed |
| WO-2022159439-A2 | MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS | JP LABORATORIES, INC. (US) | 2022-07-28 | — | — | WO | claimed |
| EP-3365898-B1 | USE OF HYDROXYIMINOALCANI ACID AS ANTI-NITRIC AGENTS IN REDUCTIVE REEXTRACTION PROCESSES FOR PLUTONIUM | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2019-11-13 | — | — | EP | disclosed |
| US-10354765-B2 | Use of hydroxyiminoalkanoic acids as anti-nitrous agents in operations of reductive stripping of plutonium | Commissariat à l'énergie atomique et aux energies alternatives (FR) | 2019-07-16 | — | — | US | disclosed |
| EP-2279291-B1 | COFERONS AND METHODS OF MAKING AND USING THEM | UNIV CORNELL (US) | 2019-07-03 | — | — | EP | disclosed |
| EP-2279291-B1 | COFERONS AND METHODS OF MAKING AND USING THEM | UNIV CORNELL (US) | 2019-07-03 | — | — | EP | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | PURDUE RESEARCH FOUNDATION (US) | 2011-10-27 | — | — | US | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20100120730-A1 | 6-BENZYL-2,3,4,7-TETRAHYDRO-INDOLO [2,3-C] QUINOLINE COMPOUNDS USEFUL AS PDE5 INHIBITORS | NYCOMED GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20100120730-A1 | 6-BENZYL-2,3,4,7-TETRAHYDRO-INDOLO [2,3-C] QUINOLINE COMPOUNDS USEFUL AS PDE5 INHIBITORS | NYCOMED GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| WO-2010015589-A1 | BENZYL-SUBSTITUTED TETRACYCLIC HETEROCYCLIC COMPOUNDS AS PDE5 INHIBITORS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015586-A2 | 2,3,4,7-TETRAHYDRO-INDOLO[2,3-C]QUINOLINE COMPOUNDS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2008095835-A1 | 6-BENZYL-2,3,4,7-TETRAHYDRO-INDOLO [2, 3-C] QUINOLINE COMPOUNDS USEFUL AS PDE5 INHIBITORS | NYCOMED GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |
| EP-1953159-A1 | 6-Benzyl-2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds useful as PDE5 inhibitors | Nycomed GmbH (DE) | 2008-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, TFRC | LMNA 471/4885TSHR 2519/4885HSD11B1 4290/4885 |
| US-20100120730-A1 | 6-BENZYL-2,3,4,7-TETRAHYDRO-INDOLO [2,3-C] QUINOLINE COMPOUNDS USEFUL AS PDE5 INHIBITORS | PDE5A, PDE3A, PDE2A | LMNA 2585/4885TSHR 3186/4885HSD11B1 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.