Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 9/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801191 | 0.94 | CHRM5 (0.46) | CHRM5CHRM3CHRM1OPRM1OPRD1 | |
| SCHEMBL1668599 | 0.91 | RXRA (0.38) | CHRM5CHRM3CHRM1OPRM1SLC6A4 | |
| SCHEMBL1668322 | 0.90 | S1PR1 (0.40) | CHRM5CHRM3CHRM1OPRM1OPRD1 | |
| SCHEMBL1668671 | 0.87 | FFAR4 (0.44) | CHRM5CHRM3CHRM1S1PR5S1PR1 | |
| SCHEMBL12800404 | 0.85 | CHRM5 (0.40) | CHRM5CHRM3CHRM1OPRM1S1PR5 | |
| SCHEMBL1668325 | 0.84 | OPRM1 (0.42) | CHRM5CHRM3CHRM1OPRM1OPRD1 | |
| SCHEMBL12800415 | 0.84 | CHRM5 (0.38) | CHRM5CHRM3CHRM1OPRM1OPRD1 | |
| SCHEMBL1668281 | 0.83 | CHRM5 (0.39) | CHRM5CHRM3CHRM1OPRM1OPRD1 | |
| SCHEMBL1668495 | 0.83 | CHRM5 (0.56) | CHRM5CHRM3CHRM1OPRM1OPRD1 | |
| SCHEMBL1668476 | 0.83 | CYP2D6 (0.46) | CHRM5CHRM3CHRM1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |