Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689401 | 0.87 | POLB (0.41) | POLBMEN1KMT2AMAPTHDAC4 | |
| SCHEMBL16688160 | 0.87 | KDM4E (0.37) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL2302566 | 0.86 | KDM4E (0.42) | MAPTTP53KDM4E | |
| SCHEMBL16688175 | 0.85 | HRH4 (0.38) | RXFP1TP53KDM4E | |
| SCHEMBL16688227 | 0.84 | RORC (0.40) | LMNAKDM4E | |
| SCHEMBL18082523 | 0.83 | PTGDR2 (0.38) | MAPTKDM4E | |
| SCHEMBL16688159 | 0.82 | PKM (0.37) | MAPTKDM4E | |
| SCHEMBL16688200 | 0.81 | KDM4E (0.36) | MAPTKDM4E | |
| SCHEMBL18082518 | 0.81 | PTGDR2 (0.35) | MAPTKDM4E | |
| SCHEMBL16261603 | 0.80 | KDM4E (0.41) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447084-B2 | Antiparisitic and pesticidal isoxazoline compounds | MERIAL, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | ACHE, PRDX1, CHRM1 | POLB 2417/4885MEN1 2319/4885KMT2A 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.