Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16693236 | 0.80 | KIF11 (0.41) | CYP17A1 | |
| SCHEMBL16693190 | 0.76 | KDM4E (0.37) | CYP17A1 | |
| SCHEMBL31335389 | 0.71 | NOTUM (0.37) | APP | |
| SCHEMBL14093011 | 0.71 | KIF11 (0.45) | CYP17A1 | |
| SCHEMBL18791161 | 0.70 | LMNA (0.38) | CYP17A1 | |
| SCHEMBL3407569 | 0.70 | CYP2A6 (0.39) | CYP17A1 | |
| SCHEMBL14117289 | 0.67 | MTNR1A (0.35) | CYP17A1 | |
| SCHEMBL13660795 | 0.67 | MGLL (0.40) | CYP17A1 | |
| SCHEMBL9103428 | 0.65 | CYP2A6 (0.45) | — | |
| SCHEMBL28913499 | 0.65 | CYP1A2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066371-A1 | SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS | FORUM PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |