Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668842 | 0.86 | KIT (0.49) | KDM4EFAAHKMT2AMEN1TPSAB1 | |
| SCHEMBL11903553 | 0.85 | RAB9A (0.51) | KDM4EFAAHKMT2AMEN1TPSAB1 | |
| SCHEMBL12685798 | 0.84 | FAAH (0.72) | KDM4EFAAHKMT2ATPSAB1CHRM4 | |
| SCHEMBL7448516 | 0.84 | TPSAB1 (0.62) | KDM4EKMT2AMEN1TPSAB1HRH3 | |
| SCHEMBL1668815 | 0.81 | SMN1; SMN2 (0.52) | KDM4EKMT2AMEN1TPSAB1NPSR1 | |
| SCHEMBL12685865 | 0.80 | MEN1 (0.79) | KDM4EFAAHKMT2AMEN1HRH3 | |
| SCHEMBL31298082 | 0.80 | NPC1 (0.58) | KDM4EFAAHKMT2AMEN1TP53 | |
| SCHEMBL7958872 | 0.78 | TPSAB1 (0.54) | KDM4EKMT2AMEN1TPSAB1HRH3 | |
| SCHEMBL1068618 | 0.78 | FAAH (0.67) | FAAHKMT2AMEN1 | |
| SCHEMBL7502026 | 0.78 | CNR1 (0.58) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |