Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620904 | 0.81 | NPSR1 (0.44) | NPSR1KDM4ECASP3TRPV3KIF11 | |
| SCHEMBL29595709 | 0.78 | NPSR1 (0.53) | NPSR1KDM4ECASP3TRPV3KIF11 | |
| SCHEMBL811160 | 0.78 | NPSR1 (0.53) | NPSR1KDM4ECASP3TRPV3KIF11 | |
| SCHEMBL2056137 | 0.78 | ENPP3 (0.62) | ENPP3ENPP1PTGS2MRGPRX4KIF11 | |
| SCHEMBL16709321 | 0.78 | CCR1 (0.61) | ENPP3ENPP1SCN9A | |
| SCHEMBL24689583 | 0.75 | CCR1 (0.64) | NPSR1KDM4ECASP3PTGS2TRPV3 | |
| SCHEMBL15495537 | 0.73 | CASP3 (0.56) | NPSR1KDM4ECASP3KIF11L3MBTL1 | |
| SCHEMBL26521094 | 0.72 | CCR1 (0.53) | NPSR1KDM4ECASP3PTGS2TRPV3 | |
| SCHEMBL26375537 | 0.72 | SCN9A (0.40) | ENPP3ENPP1PTGS2MRGPRX4TRPV3 | |
| SCHEMBL26375539 | 0.71 | ENPP3 (0.49) | ENPP3ENPP1PTGS2MRGPRX4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11129814-B2 | Antimicrobial agents | TAXIS PHARMACEUTICALS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-11129814-B2 | Antimicrobial agents | TAXIS PHARMACEUTICALS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20180338957-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-11-29 | — | — | US | disclosed |
| US-10071082-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-09-11 | — | — | US | disclosed |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-22 | — | — | US | disclosed |
| US-9458150-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458150-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150133465-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2015-05-14 | — | — | US | disclosed |
| US-20150133465-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180338957-A1 | ANTIMICROBIAL AGENTS | MRPL21, SPOUT1, LSS | NPSR1 4074/4885KDM4E 4224/4885CASP3 936/4885 |
| US-11129814-B2 | Antimicrobial agents | MRPL21, SPOUT1, LSS | NPSR1 4074/4885KDM4E 4224/4885CASP3 936/4885 |
| US-20160367531-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | NPSR1 966/4885KDM4E 4414/4885CASP3 72/4885 |
| US-10071082-B2 | Antimicrobial agents | CFTR, MRPL21, ARG1 | NPSR1 966/4885KDM4E 4414/4885CASP3 72/4885 |
| US-20150133465-A1 | ANTIMICROBIAL AGENTS | CFTR, MRPL21, ARG1 | NPSR1 966/4885KDM4E 4414/4885CASP3 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.