Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 9/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667702 | 0.85 | BRD4 (0.36) | BRD4USP2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1670150 | 0.84 | BRD4 (0.35) | FTOBRD4PDE4BPDE2APDE10A | |
| SCHEMBL1670148 | 0.84 | BRD4 (0.35) | FTOBRD4PDE4BPDE2APDE10A | |
| SCHEMBL1668122 | 0.83 | BRD4 (0.34) | BRD4USP2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1077880 | 0.76 | ALOX15 (0.37) | FTOBRD4USP2CYP1A2CYP3A4 | |
| SCHEMBL1670092 | 0.74 | ESR1 (0.34) | BRD4CYP1A2CYP3A4ALOX15CYP2C19 | |
| SCHEMBL12797222 | 0.74 | BRD4 (0.38) | BRD4USP2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1667589 | 0.73 | BRD4 (0.33) | FTOBRD4USP2CYP1A2CYP3A4 | |
| SCHEMBL1670139 | 0.73 | USP14 (0.32) | — | |
| SCHEMBL1077681 | 0.73 | ESR1 (0.38) | BRD4USP2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |