Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1961397 | 1.00 | POLB (0.42) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16704798 | 1.00 | POLB (0.42) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16704813 | 1.00 | POLB (0.42) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6099950 | 1.00 | POLB (0.42) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2263853 | 1.00 | POLB (0.42) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2265585 | 1.00 | POLB (0.42) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20434234 | 0.88 | POLB (0.39) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11225784 | 0.86 | TDP1 (0.59) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23287488 | 0.77 | POLB (0.70) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL59471 | 0.77 | POLB (0.70) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086429-A1 | POLYMER FIBERS AND PARTICLES PRODUCED BY ELECTROSPINNING OR ELECTROSPRAYING | SCALE HOLDINGS LLC (US) | 2024-04-25 | — | — | WO | claimed |
| EP-3529300-B1 | PLASTICIZED PVC ADMIXTURES WITH SURFACE MODIFYING MACROMOLECULES AND ARTICLES MADE THEREFROM | EVONIK CANADA INC (CA) | 2026-05-06 | — | — | EP | disclosed |
| EP-4698529-A1 | BLOOD BRAIN BARRIER PENETRATING SELECTIVE INHIBITORS OF ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| CN-120757496-A | Synthesis method of medicine intermediate 7-nitro-3- (trifluoromethyl) quinoline | 福建凯昕药业有限公司 | 2025-10-10 | — | — | CN | disclosed |
| US-12325788-B2 | Plasticized PVC admixtures with surface modifying macromolecules and articles made therefrom | Evonik Canada Inc. (CA) | 2025-06-10 | — | — | US | disclosed |
| EP-4551686-A1 | METHOD FOR ISOLATING PLANT STEM CELLS FROM PLANT LEAVES AND THE ASSOCIATED CELL LINES OBTAINED UTILISING THE METHOD | Green Bioactives Limited (GB) | 2025-05-14 | — | — | EP | disclosed |
| CN-119836470-A | Method for isolating plant stem cells from leaves of plants and related cell lines obtained by the method | 绿源生物活性有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119241504-A | Spiroindoline inhibitors of KIF18A | 沃拉斯查疗法公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20240360139-A1 | BLOOD BRAIN BARRIER PENETRATING SELECTIVE INHIBITORS OF ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. | 2024-10-31 | — | — | US | disclosed |
| US-20240351984-A1 | INDOLINE COMPOUNDS FOR INHIBITING KIF18A | VOLASTRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | US | disclosed |
| WO-2024008874-A1 | METHOD FOR ISOLATING PLANT STEM CELLS FROM PLANT LEAVES AND THE ASSOCIATED CELL LINES OBTAINED UTILISING THE METHOD | GREEN BIOACTIVES LIMITED (GB) | 2024-01-11 | — | — | WO | disclosed |
| US-11821112-B1 | Polymer fibers and particles produced by electrospinning or electrospraying | SCALE HOLDINGS LLC (US) | 2023-11-21 | — | — | US | disclosed |
| EP-3455269-B1 | IMPLANTABLE GLUCOSE SENSORS HAVING A BIOSTABLE SURFACE | EVONIK CANADA INC (CA) | 2023-09-20 | — | — | EP | disclosed |
| CN-116271090-A | DNA nano cage with TLR9 agonist activity and application thereof in preparation of antitumor drugs | 山东大学 | 2023-06-23 | — | — | CN | disclosed |
| US-20230147507-A1 | INDOLINE COMPOUNDS FOR INHIBITING KIF18A | VOLASTRA THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| CN-115843821-A | Application of glyceraldehyde phosphate in preparation of preparation for improving disease resistance of plants | 中国农业大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-110167995-B | Plasticized PVC compounds having surface-modified macromolecules and articles made therefrom | 界面生物公司 | 2022-07-01 | — | — | CN | disclosed |
| US-20210395463-A1 | CONTROL OF POLYMER ARCHITECTURES BY LIVING RING-OPENING METATHESIS COPOLYMERIZATION | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-12-23 | — | — | US | disclosed |
| US-11053356-B2 | Control of polymer architectures by living ring-opening metathesis copolymerization | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-07-06 | — | — | US | disclosed |
| US-9029457-B2 | Silica-supported oligomeric hybrid materials | THE UNIVERSITY OF KANSAS (US) | 2015-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240351984-A1 | INDOLINE COMPOUNDS FOR INHIBITING KIF18A | KIF18A, KIF18B, KIF2C | POLB 1120/4885TDP1 380/4885APEX1 3044/4885 |
| US-20230147507-A1 | INDOLINE COMPOUNDS FOR INHIBITING KIF18A | KIF18A, KIF18B, KIF2C | POLB 1120/4885TDP1 380/4885APEX1 3044/4885 |
| US-20240360139-A1 | BLOOD BRAIN BARRIER PENETRATING SELECTIVE INHIBITORS OF ROCK2 PROTEIN KINASES AND USES THEREOF | ROCK2, ROCK1, MYLK3 | POLB 3562/4885TDP1 1845/4885APEX1 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.