Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 4/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346112 | 0.88 | CTRC (0.61) | CTRCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL476659 | 0.83 | CTRC (0.62) | CTRCALPLALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8908899 | 0.83 | TPMT (0.50) | CTRCALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL16710006 | 0.83 | ADORA3 (0.52) | CTRCADORA3DHODH | |
| SCHEMBL2259170 | 0.80 | CTRC (0.58) | CTRCALPLALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL10918130 | 0.80 | CTRC (1.00) | CTRCALPLALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29408192 | 0.79 | CTRC (0.48) | CTRCALDH1A1KDM4EHPGDGAA | |
| SCHEMBL22658051 | 0.79 | CTRC (0.48) | CTRCALDH1A1KDM4EHPGDGAA | |
| SCHEMBL14919880 | 0.79 | SCN9A (0.64) | DHODHMCL1 | |
| SCHEMBL17689302 | 0.79 | CTRC (0.57) | CTRCALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242938-B2 | Glycine reuptake inhibitor and use thereof | BEIJING MEDISAN TECHNOLOGY CO., LTD (CN) | 2016-01-26 | — | — | US | disclosed |
| US-20150133497-A1 | GLYCINE REUPTAKE INHIBITOR AND USE THEREOF | BEIJING MEDISAN TECHNOLOGY CO., LTD. (CN) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133497-A1 | GLYCINE REUPTAKE INHIBITOR AND USE THEREOF | SLC6A2, SLC6A5, SLC6A4 | CTRC 1271/4885ALPL 4310/4885ALDH1A1 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.