Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863736 | 0.88 | TRPV4 (0.54) | TRPV4EGLN2 | |
| SCHEMBL20257118 | 0.83 | TRPV4 (0.39) | TRPV4IDO1EGLN2PDE4APDE4B | |
| SCHEMBL16707068 | 0.82 | CYP1A2 (0.33) | TRPV4 | |
| SCHEMBL20257119 | 0.80 | CYP4F2 (0.39) | TRPV4PDE4APDE4BPDE4C | |
| SCHEMBL30933437 | 0.78 | ALDH1A1 (0.40) | TRPV4EGLN2 | |
| SCHEMBL13863899 | 0.78 | CES2 (0.34) | ESR1ESR2 | |
| SCHEMBL15603837 | 0.77 | TRPV4 (0.40) | TRPV4EGLN2ESR1ESR2 | |
| SCHEMBL16604331 | 0.77 | TRPV4 (0.47) | TRPV4IDO1EGLN2PDE4APDE4B | |
| SCHEMBL30332317 | 0.77 | ESR1 (0.51) | TRPV4IDO1EGLN2PDE4APDE4B | |
| SCHEMBL20730664 | 0.76 | PDE4A (0.35) | TRPV4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862887-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-01-09 | — | — | US | disclosed |
| US-20150129800-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150129800-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | CCND2, CFD, CRY1 | TRPV4 1144/4885IDO1 1057/4885EGLN2 4206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.