Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 6/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668671 | 0.95 | FFAR4 (0.44) | CHRM5CHRM1CHRM3FFAR4FFAR1 | |
| SCHEMBL12801208 | 0.91 | FFAR4 (0.47) | CHRM5CHRM1CHRM3FFAR4FFAR1 | |
| SCHEMBL1668495 | 0.90 | CHRM5 (0.56) | CHRM5CHRM1CHRM3SIGMAR1 | |
| SCHEMBL12801191 | 0.86 | CHRM5 (0.46) | CHRM5CHRM1CHRM3APPRXRA | |
| Trifluoroacetic Acid SCHEMBL1668616 | 0.82 | FFAR4 (0.43) | FFAR4FFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL12801209 | 0.81 | OPRD1 (0.47) | FFAR4 | |
| SCHEMBL1668720 | 0.81 | CHRM5 (0.43) | CHRM5CHRM1CHRM3S1PR5RXRA | |
| Hydrochloric Acid SCHEMBL1668222 | 0.81 | FFAR1 (0.43) | FFAR4FFAR1PTGER1PTGER4PTGER3 | |
| SCHEMBL12800404 | 0.77 | CHRM5 (0.40) | CHRM5CHRM1CHRM3FFAR1S1PR5 | |
| SCHEMBL1669343 | 0.77 | OPRD1 (0.40) | CHRM5CHRM1CHRM3FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |