Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668421 | 0.98 | FFAR4 (0.37) | FFAR4APPPOLBPKMOPRM1 | |
| SCHEMBL12800404 | 0.85 | CHRM5 (0.40) | APPOPRM1RXRACHRM5CHRM1 | |
| SCHEMBL1668622 | 0.85 | OPRD1 (0.36) | FFAR4APPOPRM1 | |
| SCHEMBL1668419 | 0.83 | RXRA (0.38) | FFAR4APPOPRM1KDM4ERXRA | |
| SCHEMBL1668486 | 0.82 | SMN1; SMN2 (0.43) | FFAR4APPOPRM1RXRACHRM5 | |
| SCHEMBL1668599 | 0.81 | RXRA (0.38) | FFAR4APPOPRM1RXRACHRM5 | |
| SCHEMBL12800792 | 0.81 | SMN1; SMN2 (0.31) | POLBPKMOPRM1KDM4ELMNA | |
| SCHEMBL12800812 | 0.80 | LMNA (0.32) | POLBPKMOPRM1KDM4ELMNA | |
| SCHEMBL12801191 | 0.80 | CHRM5 (0.46) | APPOPRM1RXRACHRM5CHRM1 | |
| SCHEMBL12800418 | 0.80 | OPRM1 (0.40) | APPOPRM1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |