Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469655 | 0.85 | CES2 (0.63) | CES2CES1KCNN4ALDH1A1LMNA | |
| SCHEMBL1671676 | 0.85 | CES2 (0.63) | CES2CES1KCNN4ALDH1A1LMNA | |
| SCHEMBL30670483 | 0.85 | CES2 (0.63) | CES2CES1KCNN4ALDH1A1LMNA | |
| SCHEMBL11354965 | 0.85 | CES2 (0.63) | CES2CES1KCNN4ALDH1A1LMNA | |
| Benzylic Acid SCHEMBL7559896 | 0.78 | LMNA (0.67) | CES2CES1CYP2C9ALDH1A1CYP2D6 | |
| SCHEMBL1670874 | 0.78 | CES2 (0.45) | CES2CES1KCNN4ALDH1A1HTT | |
| SCHEMBL28905887 | 0.76 | KCNN4 (0.56) | CES2CES1CYP2C9KCNN4ALDH1A1 | |
| Benzylic Acid SCHEMBL7066 | 0.75 | CYP2C9 (0.74) | CYP2C9KCNN4ALDH1A1HTTMCOLN3 | |
| Benzylic Acid SCHEMBL28230036 | 0.74 | CYP2C9 (0.58) | CYP2C9KCNN4ALDH1A1HTTCYP2D6 | |
| Benzylic Acid SCHEMBL1680669 | 0.73 | CYP2C9 (0.71) | CYP2C9KCNN4ALDH1A1HTTMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |