SCHEMBL16709778

SCHEMBL16709778

C=Cc1c(Sc2ccc(SC)cc2)cc(Sc2ccc(SC)cc2)cc1Sc1ccc(SC)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 8/20 0.37
SLC6A2 P23975 4/20 0.37
SLC6A3 Q01959 4/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP1A1 P04798 4/20 0.32
CYP1A2 P05177 4/20 0.32
CYP1B1 Q16678 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16709712 0.81 MAOA (0.35) ALDH1A1
SCHEMBL16709701 0.80 SLC6A4 (0.36) SLC6A4SLC6A2SLC6A3ALDH1A1CYP1A1
SCHEMBL16709764 0.75 LMNA (0.41) ALDH1A1CYP1A2
SCHEMBL16709773 0.74 ALDH1A1 (0.52) ALDH1A1CYP1A1CYP1A2CYP1B1
SCHEMBL7033576 0.72 ALDH1A1 (0.50) SLC6A4SLC6A2SLC6A3ALDH1A1CYP1A1
SCHEMBL16709783 0.70 ALDH1A1 (0.36) SLC6A4SLC6A2SLC6A3ALDH1A1
SCHEMBL28051461 0.68 DHFR (0.43) ALDH1A1CYP1A2
SCHEMBL26861181 0.67 MAPT (0.42) SLC6A4SLC6A2SLC6A3ALDH1A1CYP1A2
SCHEMBL98657 0.66 ALDH1A1 (0.58) ALDH1A1CYP1A1CYP1A2CYP1B1
SCHEMBL7319023 0.65 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015068839-A1 POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL 新日鉄住金化学株式会社 2015-05-14 WO disclosed