Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16714148 | 0.89 | CYP1A2 (0.59) | ADORA3LMNANPC1ALDH1A1CYP1A2 | |
| SCHEMBL16709851 | 0.84 | ADORA3 (0.52) | ADORA3LMNAALDH1A1CYP1A2GMNN | |
| SCHEMBL16728897 | 0.79 | CYP1A2 (0.53) | ADORA3LMNAALDH1A1CYP1A2GMNN | |
| SCHEMBL16705800 | 0.78 | ALDH1A1 (0.50) | LMNANPC1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8405218 | 0.77 | CYP1A2 (0.72) | ADORA3LMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16698002 | 0.76 | KDM4E (0.52) | LMNAALDH1A1TSHR | |
| SCHEMBL20267745 | 0.75 | CYP1A2 (0.64) | ADORA3LMNAALDH1A1CYP1A2TSHR | |
| SCHEMBL11288991 | 0.75 | ALDH1A1 (0.57) | ADORA3LMNAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2833745 | 0.73 | CYP1A2 (0.61) | ADORA3LMNANPC1ALDH1A1CYP1A2 | |
| SCHEMBL30831837 | 0.73 | LMNA (0.53) | ADORA3LMNANPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988322-B2 | Process for fluorinating compounds | DOW AGROSCIENCES LLC (US) | 2018-06-05 | — | — | US | disclosed |
| US-9878983-B2 | Process for fluorinating compounds | DOW AGROSCIENCES LLC (US) | 2018-01-30 | — | — | US | disclosed |
| US-20170066721-A1 | PROCESS FOR FLUORINATING COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-03-09 | — | — | US | disclosed |
| US-20150133672-A1 | PROCESS FOR FLUORINATING COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066721-A1 | PROCESS FOR FLUORINATING COMPOUNDS | NEU4, NMBR, SNRPF | ADORA3 2486/4885LMNA 3086/4885NPC1 94/4885 |
| US-20150133672-A1 | PROCESS FOR FLUORINATING COMPOUNDS | CYP2F1, FLI1, PFAS | ADORA3 3828/4885LMNA 2165/4885NPC1 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.