Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | TPMT | P51580 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115150 | 0.91 | MEP1B (0.39) | ALDH1A1HSD17B10KDM4EMEP1BACLY | |
| SCHEMBL16712267 | 0.90 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EMEP1BKMO | |
| SCHEMBL119198 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EMEP1BKMO | |
| SCHEMBL1223251 | 0.88 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4EMEP1BKMO | |
| SCHEMBL16712268 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HSD17B10KDM4EMEP1BKMO | |
| SCHEMBL119850 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EMEP1BKMO | |
| SCHEMBL13075707 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EMEP1BKMO | |
| SCHEMBL1397100 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4EMEP1BKMO | |
| SCHEMBL1115268 | 0.81 | TAS1R3 (0.39) | ALDH1A1HSD17B10KDM4EMEP1BTPMT | |
| SCHEMBL16712292 | 0.81 | MEP1B (0.38) | ALDH1A1HSD17B10KDM4EMEP1BTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279178-B1 | 2-(substituted phenyl)-6-hydroxy- or alkoxy-5-substituted-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2015-05-20 | — | — | EP | claimed |