SCHEMBL16715013

SCHEMBL16715013

O=C(O)NNC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.37
ADAM17 P78536 1/20 0.37
KMT2A Q03164 3/20 0.36
KCNA5 P22460 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
AGTR2 P50052 1/20 0.35
CASP1 P29466 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
FKBP1A P62942 2/20 0.35
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16715012 1.00 MMP1 (0.37) MMP1ADAM17KMT2AKCNA5ALDH1A1
SCHEMBL16611662 1.00 MMP1 (0.37) MMP1ADAM17KMT2AKCNA5ALDH1A1
SCHEMBL15208236 0.92 GAA (0.39) MMP1ADAM17KMT2AALDH1A1MEN1
SCHEMBL20402405 0.92 GAA (0.39) MMP1ADAM17KMT2AALDH1A1MEN1
SCHEMBL14746514 0.91 POLB (0.36) MMP1ADAM17KCNA5SMN1; SMN2FKBP1A
SCHEMBL15207067 0.91 POLB (0.36) MMP1ADAM17KCNA5SMN1; SMN2FKBP1A
SCHEMBL15207251 0.90 ALDH1A1 (0.42) KMT2AALDH1A1MEN1LMNAHTT
SCHEMBL15365099 0.90 MMP1 (0.35) MMP1ADAM17KCNA5CASP1SMN1; SMN2
SCHEMBL16611903 0.90 GAA (0.39) MMP1ADAM17
SCHEMBL16611901 0.90 GAA (0.39) MMP1ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-10-19 US disclosed
US-11731971-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2023-08-22 US disclosed
US-20210371419-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND MEIJI SEIKA PHARMA CO., LTD. (JP) 2021-12-02 US disclosed
US-9181250-B2 Beta-lactamase inhibitor and process for preparing the same MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-11-10 US disclosed
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-05-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11731971-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 MMP1 196/4885ADAM17 2822/4885KMT2A 4162/4885
US-20150141401-A1 NOVEL BETA-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME ME1, FN1, FNTB MMP1 115/4885ADAM17 1006/4885KMT2A 2671/4885
US-20210371419-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 MMP1 196/4885ADAM17 2822/4885KMT2A 4162/4885
US-20230331724-A1 PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND FN1, BMP1, AZI2 MMP1 196/4885ADAM17 2822/4885KMT2A 4162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.