Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16716582 | 0.68 | TAS2R8 (0.37) | CA12CA1CA2CA3CA4 | |
| SCHEMBL16716546 | 0.65 | TAS2R8 (0.68) | KMT2A | |
| SCHEMBL16357866 | 0.64 | NPC1 (0.51) | CA12CA1CA2CA3CA4 | |
| SCHEMBL16716496 | 0.62 | TAS2R8 (0.64) | — | |
| SCHEMBL10090180 | 0.62 | EPHX1 (0.65) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3362410 | 0.60 | HPGD (0.51) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10090330 | 0.59 | HDAC1 (0.55) | CA12CA1CA2CA3CA4 | |
| SCHEMBL556793 | 0.59 | MEN1 (0.64) | L3MBTL1KMT2AMAPT | |
| SCHEMBL8533502 | 0.58 | TSHR (0.69) | L3MBTL1KDM4EKMT2AHPGDNPC1 | |
| SCHEMBL12500219 | 0.58 | KDM4E (0.71) | CA2MAPK1L3MBTL1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487169-B1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | SENOMYX INC (US) | 2015-05-20 | — | — | EP | disclosed |