Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 5/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16729326 | 0.85 | JAK2 (0.44) | ALDH1A1TSHRGRM5JAK2JAK1 | |
| SCHEMBL16718838 | 0.74 | KDM4E (0.44) | KCNQ3KCNQ2KDM4EHSD17B10BTK | |
| SCHEMBL16718864 | 0.73 | GRM4 (0.41) | BTKJAK2JAK1 | |
| SCHEMBL16718884 | 0.71 | JAK2 (0.43) | IRAK4JAK2JAK1 | |
| SCHEMBL16718861 | 0.71 | ACKR3 (0.45) | JAK2JAK1 | |
| SCHEMBL16718850 | 0.71 | GRM4 (0.47) | JAK2JAK1HSD11B1 | |
| SCHEMBL16718807 | 0.67 | JAK2 (0.45) | ALDH1A1TSHRJAK2JAK1 | |
| SCHEMBL25261273 | 0.67 | KCNQ3 (0.43) | ALDH1A1TSHRKCNQ3KCNQ2HSD11B1 | |
| SCHEMBL30044843 | 0.67 | GRM5 (0.84) | GRM5KDM4E | |
| SCHEMBL17460376 | 0.66 | KCNQ3 (0.41) | ALDH1A1KCNQ3KCNQ2IRAK4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073267-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE | CALITOR SCIENCES, LLC (US) | 2015-05-21 | — | — | WO | disclosed |