Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209132 | 0.82 | TAAR1 (0.40) | ESR2HSD17B1HSD17B2MAPTTAAR1 | |
| SCHEMBL16719582 | 0.82 | HSD17B1 (0.47) | ESR2HSD17B1HSD17B2LMNA | |
| SCHEMBL16719325 | 0.80 | PTPN5 (0.47) | MAPTALOX15ALOX12PTPN5 | |
| SCHEMBL16719523 | 0.79 | HSD17B1 (0.40) | ESR2HSD17B1HSD17B2 | |
| SCHEMBL2013350 | 0.79 | TAAR1 (0.38) | ESR2HSD17B1HSD17B2TAAR1MEN1 | |
| SCHEMBL16720374 | 0.79 | CNR2 (0.51) | MAPTALOX15ALOX12THRB | |
| SCHEMBL16719911 | 0.79 | ALOX5 (0.49) | ESR2ALOX15ALOX12TAAR1FYN | |
| SCHEMBL2012945 | 0.79 | ACHE (0.39) | ESR2MAPTSMN1; SMN2ALOX15TP53 | |
| SCHEMBL16720447 | 0.79 | ESR2 (0.39) | ESR2HSD17B1HSD17B2MAPTTAAR1 | |
| SCHEMBL27707563 | 0.79 | TAAR1 (0.40) | ESR2HSD17B1HSD17B2MAPTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |