Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719582 | 0.82 | HSD17B1 (0.47) | CA12CA9 | |
| SCHEMBL5634702 | 0.82 | ACHE (0.39) | CNR2CNR1ACHE | |
| SCHEMBL1045097 | 0.79 | AKR1C3 (0.44) | CNR2CNR1ACHERPS6KA3 | |
| SCHEMBL16719911 | 0.79 | ALOX5 (0.49) | CA12CA9ALOX15ALOX12 | |
| SCHEMBL16720132 | 0.79 | ESR2 (0.46) | ALOX15ALOX12MAPTTHRB | |
| SCHEMBL2377419 | 0.79 | HDAC4 (0.50) | CNR2CNR1ABCB1RPS6KA3ACLY | |
| SCHEMBL16719963 | 0.79 | CNR2 (0.41) | CNR2CNR1ALOX15ALOX12 | |
| SCHEMBL9988102 | 0.78 | BACE1 (0.38) | CA12CA9ALOX15ALOX12ACHE | |
| SCHEMBL29035128 | 0.77 | CNR2 (0.60) | CNR2CNR1CA12CA9ALOX15 | |
| SCHEMBL159940 | 0.77 | ALDH1A1 (0.54) | CNR2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |