Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | DDO | Q99489 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987691 | 0.85 | KDM4E (0.39) | — | |
| SCHEMBL8131456 | 0.83 | BCAT1 (0.36) | BCAT1CES2BCHECES1CCNE2 | |
| SCHEMBL16720252 | 0.81 | CA1 (0.34) | CES2CES1 | |
| SCHEMBL2053580 | 0.79 | HSD11B1 (0.35) | BCAT1CCNE2CCNE1CDK2SLC9A1 | |
| SCHEMBL2014556 | 0.79 | BCAT1 (0.33) | BCAT1CCNE2CCNE1CDK2 | |
| SCHEMBL2373481 | 0.77 | ALDH1A1 (0.44) | — | |
| SCHEMBL6367917 | 0.77 | ALDH1A1 (0.44) | CES2BCHECES1 | |
| SCHEMBL2049472 | 0.76 | HSD11B1 (0.42) | BCAT1CCNE2CCNE1CDK2 | |
| SCHEMBL6669373 | 0.75 | CYP1A2 (0.45) | — | |
| SCHEMBL5673742 | 0.75 | CYP1A2 (0.33) | BCAT1CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |