SCHEMBL2014556

SCHEMBL2014556

Fc1cccc(-c2cc[c]cc2Cl)c1F

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 1/20 0.33
CCNE2 O96020 1/20 0.33
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
EIF4E P06730 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
ELANE P08246 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5673742 0.86 CYP1A2 (0.33) BCAT1CCNE2CCNE1CDK2CYP11B1
SCHEMBL434626 0.85 KCNN4 (0.36) ELANECYP1A2CYP2C9CYP2C19TDP1
SCHEMBL8131456 0.83 BCAT1 (0.36) BCAT1CCNE2CCNE1CDK2
SCHEMBL2050040 0.81 TAAR1 (0.32) TAAR1
SCHEMBL28083402 0.79 KMO (0.37) TAAR1ELANECYP1A2CYP2C9CYP2C19
SCHEMBL16720156 0.79 BCAT1 (0.33) BCAT1CCNE2CCNE1CDK2
SCHEMBL2053580 0.79 HSD11B1 (0.35) BCAT1CCNE2CCNE1CDK2
SCHEMBL1135190 0.78
SCHEMBL1810776 0.77 CYP2A6 (0.44) TDP1
SCHEMBL2049472 0.76 HSD11B1 (0.42) BCAT1CCNE2CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO disclosed
EP-2547687-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-01-23 EP disclosed
EP-2513067-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2012-10-24 EP disclosed
WO-2011113820-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2011-09-22 WO disclosed
WO-2011073145-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2011-06-23 WO disclosed