SCHEMBL16726453

SCHEMBL16726453

Cc1ccc2c(oc3ncccc32)c1N1c2ccccc2N(C(C)C)[C@@H]1C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.32
▸ CYP1B1 Q16678 1/20 0.32
▸ PIK3CA P42336 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16726482 0.92 — —
SCHEMBL16726513 0.92 — —
SCHEMBL20349250 0.90 CYP1A2 (0.31) CYP1A2CYP1B1PIK3CA
SCHEMBL16716135 0.90 PIK3CA (0.32) CYP1A2CYP1B1PIK3CA
SCHEMBL16726454 0.87 — —
SCHEMBL23729265 0.85 KDM4E (0.32) CYP1A2CYP1B1PIK3CAKDM4EALDH1A1
SCHEMBL16726451 0.85 KDM4E (0.32) CYP1A2CYP1B1PIK3CAKDM4EALDH1A1
SCHEMBL26300860 0.85 PIK3CA (0.34) PIK3CAKDM4EALDH1A1
SCHEMBL16716122 0.85 — —
SCHEMBL20356283 0.85 PIK3CA (0.32) CYP1A2CYP1B1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-12022727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-06-25 — — US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 — — US disclosed
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-25 — — US disclosed
US-11844267-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-12 — — US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 — — US disclosed
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 — — US disclosed
US-20230389410-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 — — US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-11818946-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 — — US disclosed
US-20190036040-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-01-31 — — US disclosed
EP-3435438-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-01-30 — — EP disclosed
US-20190019963-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-01-17 — — US disclosed
US-10033000-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 — — US disclosed
US-10033000-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-07-24 — — US disclosed
US-20180190914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-05 — — US disclosed
US-20180190914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-05 — — US disclosed
EP-2874192-B1 Organic eletroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2017-05-10 — — EP disclosed
US-20150137096-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 — — US disclosed
US-20150137096-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019963-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EML4, LEF1 CYP1A2 1237/4885CYP1B1 2386/4885PIK3CA 4803/4885
US-11844267-B2 Organic electroluminescent materials and devices L1CAM, LEF1, EPCAM CYP1A2 1025/4885CYP1B1 2314/4885PIK3CA 4714/4885
US-20240025934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, RO60, LIFR CYP1A2 3956/4885CYP1B1 4203/4885PIK3CA 3873/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND CYP1A2 2052/4885CYP1B1 2965/4885PIK3CA 4369/4885
US-10033000-B2 Organic electroluminescent materials and devices LSM8, OPRM1, OXER1 CYP1A2 1425/4885CYP1B1 1734/4885PIK3CA 4199/4885
US-11818946-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, AOC3 CYP1A2 224/4885CYP1B1 367/4885PIK3CA 4677/4885
US-20190036040-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MCU, ICMT, ORAI2 CYP1A2 4487/4885CYP1B1 4814/4885PIK3CA 2518/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 CYP1A2 656/4885CYP1B1 1203/4885PIK3CA 4182/4885
US-12022727-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 CYP1A2 786/4885CYP1B1 991/4885PIK3CA 3838/4885
US-20180190914-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, OCIAD1, ICOSLG CYP1A2 3320/4885CYP1B1 4115/4885PIK3CA 2549/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP CYP1A2 167/4885CYP1B1 437/4885PIK3CA 4788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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