Sugi Predict

Sugi Predict / Compounds / SCHEMBL1672801

SCHEMBL1672801

SCHEMBL1672801

NCc1c(O)ccc2c1Oc1cc(O)ccc1C21OC(=O)c2ccc(C(=O)O)cc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 10/20 0.49
▸ MAPT P10636 3/20 0.49
▸ HPGD P15428 2/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ HTT P42858 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ CYP2C19 P33261 1/20 0.49
▸ RECQL P46063 1/20 0.49
▸ BLM P54132 1/20 0.49
▸ SMAD3 P84022 1/20 0.49
▸ PRMT1 Q99873 1/20 0.49
▸ ACE2 Q9BYF1 1/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ GNG2 P59768 1/20 0.39
▸ GNB1 P62873 1/20 0.39
▸ ALOX12 P18054 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ BRCA1 P38398 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78588 0.93 FTO (0.53) FTOMAPTHPGDMEN1HTT
SCHEMBL499201 0.86 FTO (0.68) FTOMAPTHPGDMEN1HTT
Hydrochloric Acid SCHEMBL9650959 0.85 FTO (0.67) FTOMAPTHPGDMEN1HTT
Hydrochloric Acid SCHEMBL3996680 0.85 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL29353864 0.84 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL29613006 0.84 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL20833 0.84 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL1672604 0.84 FTO (0.43) FTOMAPTHPGDMEN1HTT
Water SCHEMBL25244476 0.83 FTO (0.66) FTOMAPTHPGDMEN1HTT
Ammonia Solution, Strong SCHEMBL29083295 0.83 FTO (0.66) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504496-B2 Water-soluble rhodamine dye conjugates APPLIED BIOSYSTEMS, LLC 2009-03-17 — — US claimed
US-8030096-B2 Water-soluble rhodamine dyes conjugates APPLIED BIOSYSTEMS LLC (US) 2011-10-04 — — US disclosed
US-20110081688-A1 Water-Soluble Rhodamine Dyes Conjugates Life Technologies Corporation (US) 2011-04-07 — — US disclosed
US-20100304381-A1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS Life Technologies Corporation (US) 2010-12-02 — — US disclosed
US-7795042-B2 Water-soluble rhodamine dye conjugates APPLIED BIOSYSTEMS, LLC (US) 2010-09-14 — — US disclosed
US-7687236-B2 Fluorescent nucleobase conjugates having anionic linkers APPLIED BIOSYSTEMS, LLC (US) 2010-03-30 — — US disclosed
US-20090305433-A1 Water-Soluble Rhodamine Dye Conjugates APPLIED BIOSYSTEMS INC. (US) 2009-12-10 — — US disclosed
EP-1317464-B1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS APPLERA CORP (US) 2009-05-13 — — EP disclosed
US-20090092986-A1 Fluorescent Nucleobase Conjugates Having Anionic Linkers APPLIED BIOSYSTEMS INC. (US) 2009-04-09 — — US disclosed
US-7504496-B2 Water-soluble rhodamine dye conjugates APPLIED BIOSYSTEMS, LLC 2009-03-17 — — US disclosed
WO-2004029578-A2 ENERGY TRANSFER DYES, TERMINATORS AND USE THEREOF AMERSHAM BIOSCIENCES CORP (US) 2004-04-08 — — WO disclosed
EP-1141137-B1 WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF APPLERA CORP (US) 2003-10-08 — — EP disclosed
EP-1317464-A2 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS Applera Corporation (US) 2003-06-11 — — EP disclosed
US-20030055257-A1 Water-soluble rhodamine dye conjugates APPLERA CORPORATION (US) 2003-03-20 — — US disclosed
US-20020102590-A1 Fluorescent nucleobase conjugates having anionic linkers PE CORPORATION (NY) (US) 2002-08-01 — — US disclosed
WO-2002030944-A2 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS APPLERA CORPORATION (US) 2002-04-18 — — WO disclosed
US-6372907-B1 LABELLED RHODAMINE DYE-POLYPEPTIDE CONJUGATE, OR SALT THEREOF, COMPRISING RHODAMINE-TYPE PARENT XANTHENE RING SUBSTITUTED AT XANTHENE C-9 CARBON WITH SUBSTITUTED PHENYL RING APPTERA CORPORATION 2002-04-16 — — US disclosed
EP-1141137-A1 WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF Applera Corporation (US) 2001-10-10 — — EP disclosed
WO-2001032783-A1 WATER-SOLUBLE RHODAMINE DYES AND CONJUGATES THEREOF APPLERA CORPORATION (US) 2001-05-10 — — WO disclosed
US-6191278-B1 COMPRISING A RHODAMINE-TYPE PARENT RING HAVING ATTACHED TO THE XANTHENE C9 CARBON A PHENYL GROUP THAT IS SUBSTITUTED WITH CARBOXY OR SULFONATE GROUP, ONE TO THREE AMINOPYRIDINIUM GROUPS AND AN ALKYL- OR ARYLTHIO, AND OPTIONALLY OTHER GROUPS PE CORPORATION 2001-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055257-A1 Water-soluble rhodamine dye conjugates SLC43A3, ABCG2, TARBP1 FTO 2304/4885MAPT 1605/4885HPGD 2451/4885
US-20090305433-A1 Water-Soluble Rhodamine Dye Conjugates SLC43A3, ABCG2, TARBP1 FTO 2304/4885MAPT 1605/4885HPGD 2451/4885
US-20100304381-A1 FLUORESCENT NUCLEOBASE CONJUGATES HAVING ANIONIC LINKERS DNTT, DUT, NT5C3B FTO 341/4885MAPT 4071/4885HPGD 3173/4885
US-20110081688-A1 Water-Soluble Rhodamine Dyes Conjugates SLC43A3, ABCG2, TARBP1 FTO 2495/4885MAPT 1604/4885HPGD 2638/4885
US-20020102590-A1 Fluorescent nucleobase conjugates having anionic linkers DNTT, DUT, NT5C3B FTO 341/4885MAPT 4071/4885HPGD 3173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.