Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | GNG2 | P59768 | 1/20 | 0.40 |
| ▸ | GNB1 | P62873 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672801 | 0.93 | FTO (0.49) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL499201 | 0.87 | FTO (0.68) | FTOMAPTHPGDMEN1HTT | |
| Hydrochloric Acid SCHEMBL3996680 | 0.86 | FTO (0.67) | FTOMAPTHPGDMEN1HTT | |
| Hydrochloric Acid SCHEMBL9650959 | 0.86 | FTO (0.67) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL29996062 | 0.84 | FTO (0.69) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL29358729 | 0.84 | FTO (0.69) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL20095 | 0.84 | FTO (0.69) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL29838678 | 0.84 | FTO (0.69) | FTOMAPTHPGDMEN1HTT | |
| Water SCHEMBL25247555 | 0.83 | FTO (0.67) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL23158785 | 0.83 | FTO (0.67) | FTOMAPTHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604186-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-20120196295-A1 | UV Excitable Fluorescent Energy Transfer Dyes | Life Technologies Corporation (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120172583-A1 | Oligonucleotides and Analogs Labeled with Energy Transfer Dyes | Life Technologies Corporation (US) | 2012-07-05 | — | — | US | disclosed |
| US-8129529-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | Life Technologies Corporation (US) | 2011-03-31 | — | — | US | disclosed |
| US-7888507-B2 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC | 2011-02-15 | — | — | US | disclosed |
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | APPLERA CORPORATION (US) | 2010-11-04 | — | — | US | disclosed |
| US-7825237-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100029923-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | Life Technologies Corporation (US) | 2010-02-04 | — | — | US | disclosed |
| US-7595162-B2 | Methods of labeling polynucleotides with energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-6335440-B1 | NUCLEIC ACID SEQUENCING | PE CORPORATION (NY) | 2002-01-01 | — | — | US | disclosed |
| US-20010049109-A1 | UV excitable fluorescent energy transfer dyes | APPLIED BIOSYSTEMS, LLC | 2001-12-06 | — | — | US | disclosed |
| US-6218124-B1 | FORMING DIFFERENT SIZED OLIGONUCLEOTIDES LABELED WITH ENERGY TRANSFER DYE,SEPARATING OLIGONUCLEOTIDES BASED ON SIZE, DETECTING USING ULTRAVIOLET SOURCE; FOR SEQUENCING NUCLEIC ACIDS | PE CORPORATION | 2001-04-17 | — | — | US | disclosed |
| WO-2001016369-A2 | UV EXCITABLE FLUORESCENT ENERGY TRANSFER DYES | PE CORPORATION (NY) (US) | 2001-03-08 | — | — | WO | disclosed |
| EP-0805190-B1 | Energy transfer dyes with enhanced fluorescence | PERKIN ELMER CORP (US) | 1999-12-15 | — | — | EP | disclosed |
| EP-0940450-A1 | Energy transfer dyes with enhanced fluorescence | PERKIN-ELMER CORPORATION (US) | 1999-09-08 | — | — | EP | disclosed |
| US-5945526-A | DONOR DYE COUPLED TO ACCEPTOR DYES BY NOVEL LINKER WITH AMIDE, CARBOXY ESTER OR CARBON-OXYGEN-SULFUR MOIETY; FOR EFFICIENT TRANSFER OF ENERGY; USED IN NUCLEOTIDE SEQUENCING METHODS | PERKIN-ELMER CORPORATION (US) | 1999-08-31 | — | — | US | disclosed |
| US-5863727-A | AN ACCEPTOR FLUOROPHORE EFFICIENTLY ABSORBS ENERGY EMISSION OF A LINKED DONOR XANTHENE FLUOROPHORE LABELLING A OLIGONUCLEOTIDE PRIMER; REAGENT FOR SEQUENCING NUCLEIC ACIDS | THE PERKIN-ELMER CORPORATION | 1999-01-26 | — | — | US | disclosed |
| US-5800996-A | Energy transfer dyes with enchanced fluorescence | THE PERKIN ELMER CORPORATION (US) | 1998-09-01 | — | — | US | disclosed |
| EP-0805190-A2 | Energy transfer dyes with enhanced fluorescence | PERKIN-ELMER CORPORATION (US) | 1997-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | SLC25A21, ZCCHC8, ZDHHC7 | FTO 446/4885MAPT 3461/4885HPGD 2296/4885 |
| US-20100029923-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RPS28 | FTO 454/4885MAPT 3423/4885HPGD 3645/4885 |
| US-20120196295-A1 | UV Excitable Fluorescent Energy Transfer Dyes | SLC46A1, SLC43A3, SLC25A4 | FTO 707/4885MAPT 513/4885HPGD 164/4885 |
| US-20120172583-A1 | Oligonucleotides and Analogs Labeled with Energy Transfer Dyes | RBM28, TRDMT1, RPS28 | FTO 454/4885MAPT 3423/4885HPGD 3645/4885 |
| US-20010049109-A1 | UV excitable fluorescent energy transfer dyes | SLC46A1, SLC43A3, SLC25A4 | FTO 707/4885MAPT 513/4885HPGD 164/4885 |
| US-20110077415-A1 | UV Excitable Fluorescent Energy Transfer Dyes | SLC46A1, SLC43A3, SLC25A4 | FTO 707/4885MAPT 513/4885HPGD 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.