Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13287266 | 0.84 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL16659160 | 0.84 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL8101166 | 0.84 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL14227023 | 0.84 | NOS2 (0.38) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL15539708 | 0.83 | SLC7A5 (0.46) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL11680891 | 0.83 | SLC7A5 (0.46) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL17324229 | 0.81 | GABRP (0.31) | SLC7A5 | |
| SCHEMBL16728149 | 0.79 | NOS2 (0.39) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL18314370 | 0.78 | NOS2 (0.33) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL16724765 | 0.78 | CYP3A4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376700-B2 | Methods of modifying N-termini of a peptide or protein using transferases | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150140605-A1 | ONE STEP N-TERMINAL TAGGING OF PROTEINS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140605-A1 | ONE STEP N-TERMINAL TAGGING OF PROTEINS | TRMT1, RNGTT, NSUN3 | NOS2 3584/4885NOS1 3133/4885NOS3 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.