Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.39 |
| ▸ | NOS1 | P29475 | 5/20 | 0.39 |
| ▸ | NOS3 | P29474 | 4/20 | 0.39 |
| ▸ | BHMT | Q93088 | 9/20 | 0.38 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.30 |
| ▸ | GABRE | P78334 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16724763 | 0.79 | BHMT (0.35) | NOS2NOS1NOS3BHMTBHMT2 | |
| SCHEMBL18541264 | 0.79 | BHMT (0.40) | NOS2NOS1NOS3BHMTBHMT2 | |
| SCHEMBL16728136 | 0.79 | NOS2 (0.33) | NOS2NOS1NOS3SLC7A5 | |
| SCHEMBL12681647 | 0.79 | NOS2 (0.41) | NOS2NOS1NOS3BHMTBHMT2 | |
| SCHEMBL5673786 | 0.74 | — | — | |
| SCHEMBL5672851 | 0.74 | — | — | |
| SCHEMBL15225393 | 0.74 | — | — | |
| SCHEMBL16540888 | 0.69 | NOS2 (0.47) | NOS2NOS1NOS3BHMTBHMT2 | |
| SCHEMBL10069251 | 0.69 | SLC1A3 (0.48) | NOS2NOS1NOS3BHMTBHMT2 | |
| SCHEMBL15080395 | 0.69 | SLC1A3 (0.48) | NOS2NOS1NOS3BHMTBHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376700-B2 | Methods of modifying N-termini of a peptide or protein using transferases | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150140605-A1 | ONE STEP N-TERMINAL TAGGING OF PROTEINS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140605-A1 | ONE STEP N-TERMINAL TAGGING OF PROTEINS | TRMT1, RNGTT, NSUN3 | NOS2 3584/4885NOS1 3133/4885NOS3 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.