Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719292 | 0.80 | LTA4H (0.42) | LMNADRD2DRD4DRD3POLB | |
| SCHEMBL16728377 | 0.80 | FFAR1 (0.40) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16728441 | 0.80 | LMNA (0.40) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16728463 | 0.79 | ALDH1A1 (0.41) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16721990 | 0.79 | TSHR (0.44) | ALDH1A1 | |
| SCHEMBL16719280 | 0.78 | S1PR1 (0.51) | DRD2DRD4DRD3 | |
| SCHEMBL16722639 | 0.77 | S1PR5 (0.53) | — | |
| SCHEMBL15196993 | 0.69 | HPGD (0.43) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16445529 | 0.68 | MAPT (0.52) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16728485 | 0.67 | PPARG (0.40) | LMNAMAPTALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015073556-A1 | DISUBSTITUTED PHENOXY DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | disclosed |
| WO-2015073547-A1 | DISUBSTITUTED PHENOXY AZETIDINE DERIVATIVES AS SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2015-05-21 | — | — | WO | disclosed |