Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 9/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592364 | 1.00 | MPL (0.47) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL29110854 | 1.00 | MPL (0.47) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL29431679 | 0.98 | MPL (0.49) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL112192 | 0.98 | MPL (0.49) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL15523070 | 0.96 | MPL (0.47) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL31344266 | 0.96 | MPL (0.47) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL217202 | 0.96 | MPL (0.47) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL590946 | 0.96 | MPL (0.47) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL2776938 | 0.96 | MPL (0.47) | MPLNT5EAURKAAURKBCYP1A2 | |
| SCHEMBL518440 | 0.94 | MPL (0.44) | MPLNT5EAURKAAURKBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069954-A | Photoacid coordination polymer, and preparation method and application thereof | 萍乡学院 | 2023-11-17 | — | — | CN | claimed |
| CN-107879332-B | Method for preparing graphene by stripping graphite by time-space synchronous ultrasonic ball milling method | 中南民族大学 | 2020-06-30 | — | — | CN | claimed |
| CN-107020780-B | A kind of composite fluorescent film and its preparation method and application | 南雄阳普医疗科技有限公司 | 2019-10-18 | — | — | CN | claimed |
| CN-106153585-B | A kind of sensing carbon dioxide gas probe, the production method of probe and the sensor-based system containing the probe | 河南理工大学 | 2018-10-26 | — | — | CN | claimed |
| CN-106153585-A | A kind of sensing carbon dioxide gas probe, the manufacture method of probe and the sensor-based system containing this probe | 河南理工大学 | 2016-11-23 | — | — | CN | claimed |
| US-8182595-B2 | Correcting fluid with drying indicator | SOCIETE BIC (FR) | 2012-05-22 | — | — | US | claimed |
| US-20100163799-A1 | CORRECTING FLUID WITH DRYING INDICATOR | SOCIETE BIC | 2010-07-01 | — | — | US | claimed |
| US-20080193758-A1 | Nanoscale Fluorescent Melamine Particles | MERCK PATENT GMBH (DE) | 2008-08-14 | — | — | US | claimed |
| CN-113552068-A | Rapid and accurate detection method, application and kit for isoquinoline alkaloid | 天津中新药业集团股份有限公司中新制药厂 | 2021-10-26 | — | — | CN | disclosed |
| CN-113552068-A | Rapid and accurate detection method, application and kit for isoquinoline alkaloid | 天津中新药业集团股份有限公司中新制药厂 | 2021-10-26 | — | — | CN | disclosed |
| EP-3823752-A1 | MICROFLUIDIC DEVICE FOR APPLYING PRESSURE TO A CELL ASSEMBLY | Technische Universität Wien (AT) | 2021-05-26 | — | — | EP | disclosed |
| CN-112730357-A | Optical sensing film for detecting two-dimensional distribution of carbon dioxide in sediment | 中国科学院南京地理与湖泊研究所 | 2021-04-30 | — | — | CN | disclosed |
| CN-111855767-A | Multifunctional flowing thin-layer electrochemical cell and application thereof | 安徽中医药大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-107879332-B | Method for preparing graphene by stripping graphite by time-space synchronous ultrasonic ball milling method | 中南民族大学 | 2020-06-30 | — | — | CN | disclosed |
| US-20060057220-A1 | Fine spherical particles with satisfactory molecular orientation, spherical microcapsules comprising the same and processes for producing these | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2006-03-16 | — | — | US | disclosed |
| EP-1252520-B1 | NITROREDUCTASE REPORTER GENE ASSAY INVOLVING FLUORESCENCE ENHANCEMENT | AMERSHAM BIOSCIENCES UK LTD (GB) | 2005-10-12 | — | — | EP | disclosed |
| EP-1550670-A1 | FINE SPHERICAL PARTICLES WITH SATISFACTORY MOLECULAR ORIENTATION, SPHERICAL MICROCAPSULES COMPRISING THE SAME, AND PROCESSES FOR PRODUCING THESE | National Institute of Advanced Industrial Science and Technology (JP) | 2005-07-06 | — | — | EP | disclosed |
| US-20030186348-A1 | Fluorescent detection method and reagent | GE HEALTHCARE UK LIMITED (GB) | 2003-10-02 | — | — | US | disclosed |
| EP-1252520-A2 | METHODS EMPLOYING INCREASED DYE-FLUORESCENCE UPON NITROREDUCTION | Amersham Biosciences UK Limited (GB) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001057237-A2 | METHODS EMPLOYING INCREASED DYE-FLUORESCENCE UPON NITROREDUCTION | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2001-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186348-A1 | Fluorescent detection method and reagent | BLVRB, CYB5R3, HMOX2 | MPL 4882/4885NT5E 432/4885AURKA 4167/4885 |
| US-20060057220-A1 | Fine spherical particles with satisfactory molecular orientation, spherical microcapsules comprising the same and processes for producing these | AUP1, AQP1, MAST1 | MPL 1437/4885NT5E 4299/4885AURKA 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.