SCHEMBL2977301

SCHEMBL2977301

O=c1ncc2occc2[nH]1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.42
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
FTO Q9C0B1 1/20 0.31
OGT O15294 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11842784 0.68 MAOA (0.42) MAOAMAOBFTO
SCHEMBL30752490 0.68 DAO (0.46) DAOMAOAMAOBFTOOGT
SCHEMBL1498253 0.68 POLB (0.30) POLB
SCHEMBL218085 0.66
SCHEMBL1673129 0.65 NOS1 (0.37) POLB
SCHEMBL11268792 0.64 MAPKAPK2 (0.41) DAO
SCHEMBL11829893 0.63 MAOA (0.37) MAOAMAOBPOLB
SCHEMBL3360781 0.63 DAO (0.53) DAO
SCHEMBL10417 0.63 CA12 (0.48) DAO
SCHEMBL29371690 0.63 CA12 (0.48) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222682913-U High-efficiency conveying device for pyrimidofuranone powder 江西联柏科技有限公司 2025-03-28 CN claimed
CN-221772150-U Magnetic heating stirrer for preparing pyrimidofuranone 江西联柏科技有限公司 2024-09-27 CN claimed
CN-219284742-U Pyrimidine furanone synthetic sample collector 临沂晟泰高分子材料有限公司 2023-06-30 CN claimed
CN-219186826-U Pyrimidine furanone contactless adding equipment 临沂晟泰高分子材料有限公司 2023-06-16 CN claimed
CN-115557901-A Efficient production method of pyrimidofuranone 湖北有宜新材料科技有限公司 2023-01-03 CN claimed
CN-212731311-U Layering washing device of pyrimidofuranone processing usefulness 临沂晟泰高分子材料有限公司 2021-03-19 CN claimed
US-20070213307-A1 Methods to treat autoimmune and inflammatory conditions CELMED ONCOLOGY (USA), INC. 2007-09-13 US claimed
EP-1551962-A4 MITOTIC KINESIN BINDING SITE MERCK & CO INC (US) 2007-08-01 EP claimed
EP-1359921-A4 METHODS TO TREAT AUTOIMMUNE AND INFLAMMATORY CONDITIONS NEWBIOTICS INC (US) 2006-09-06 EP claimed
EP-1551962-A2 MITOTIC KINESIN BINDING SITE Merck & Co., Inc. (US) 2005-07-13 EP claimed
WO-2004004652-A2 MITOTIC KINESIN BINDING SITE MERCK & CO., INC. (US) 2004-01-15 WO claimed
EP-1359921-A2 METHODS TO TREAT AUTOIMMUNE AND INFLAMMATORY CONDITIONS NewBiotics, Inc. (US) 2003-11-12 EP claimed
US-20020151519-A1 Methods to treat autoimmune and inflammatory conditions CELMED ONCOLOGY (USA), INC. (CA) 2002-10-17 US claimed
US-20020147175-A1 Synergistic ECTA compositions NEWBIOTICS, INC. 2002-10-10 US claimed
WO-2002056832-A2 METHODS TO TREAT AUTOIMMUNE AND INFLAMMATORY CONDITIONS NEWBIOTICS, INC. (US) 2002-07-25 WO claimed
WO-2002039952-A2 SYNERGISTIC ECTA COMPOSITIONS NEWBIOTICS, INC. (US) 2002-05-23 WO claimed
CN-222682913-U High-efficiency conveying device for pyrimidofuranone powder 江西联柏科技有限公司 2025-03-28 CN disclosed
CN-222682913-U High-efficiency conveying device for pyrimidofuranone powder 江西联柏科技有限公司 2025-03-28 CN disclosed
WO-2001007087-A2 ENZYME CATALYZED ANTI-INFECTIVE THERAPEUTIC AGENTS NEWBIOTICS, INC. (US) 2001-02-01 WO disclosed
WO-2001007454-A1 ENZYME CATALYZED THERAPEUTIC ACTIVATION NEWBIOTICS, INC. (US) 2001-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020147175-A1 Synergistic ECTA compositions ENTPD1, ENTPD2, ENPP1 DAO 1872/4885MAOA 339/4885MAOB 1040/4885
US-20020151519-A1 Methods to treat autoimmune and inflammatory conditions SSB, ENPP2, TPMT DAO 344/4885MAOA 1737/4885MAOB 1256/4885
US-20070213307-A1 Methods to treat autoimmune and inflammatory conditions SSB, ENPP2, TPMT DAO 344/4885MAOA 1737/4885MAOB 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.