Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | MC5R | P33032 | 3/20 | 0.38 |
| ▸ | MC1R | Q01726 | 3/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797839 | 1.00 | MC4R (0.38) | MC4RMC5RMC1RMC3RCTSG | |
| SCHEMBL7860951 | 0.87 | ANPEP (0.40) | MC4RMC5RMC1RMC3RMMP9 | |
| SCHEMBL14861006 | 0.87 | ANPEP (0.40) | MC4RMC5RMC1RMC3RMMP9 | |
| SCHEMBL2304374 | 0.82 | MC4R (0.39) | MC4RMC5RMC1RMC3RCTSG | |
| SCHEMBL28896045 | 0.81 | MMP9 (0.41) | MC4RMC5RMC1RMC3RMMP9 | |
| SCHEMBL7717724 | 0.77 | ALDH1A1 (0.44) | MC4R | |
| SCHEMBL22346178 | 0.77 | ALDH1A1 (0.44) | MC4R | |
| SCHEMBL10419724 | 0.77 | CTSG (0.31) | MC4RMC5RMC1RMC3RCTSG | |
| SCHEMBL537112 | 0.76 | ANPEP (0.36) | MC4RMC5RMC1RMC3REPHX2 | |
| Hydrochloric Acid SCHEMBL27842009 | 0.76 | ALDH1A1 (0.43) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222404-B1 | PROTEASE DETECTION | MOLOGIC LTD (GB) | 2018-08-01 | — | — | EP | disclosed |
| US-9376706-B2 | Protease detection | MOLOGIC LIMITED (GB) | 2016-06-28 | — | — | US | disclosed |
| US-20150152471-A1 | PROTEASE DETECTION | MOLOGIC LIMITED (GB) | 2015-06-04 | — | — | US | disclosed |
| US-8993253-B2 | Protease detection | MOLOGIC LTD (GB) | 2015-03-31 | — | — | US | disclosed |
| CN-101896272-B | Protease detection | MOLOGIC LTD | 2013-07-31 | — | — | CN | disclosed |
| US-20110086370-A1 | Protease Detection | MOLOGIC LTD (GB) | 2011-04-14 | — | — | US | disclosed |
| CN-101896272-A | Protease detection | MOLOGIC LTD | 2010-11-24 | — | — | CN | disclosed |
| EP-2222404-A2 | PROTEASE DETECTION | Mologic Ltd (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009063208-A2 | PROTEASE DETECTION | MOLOGIC LTD (GB) | 2009-05-22 | — | — | WO | disclosed |