Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15674956 | 0.85 | GPR88 (0.50) | NPSR1CNR2GPR88ALDH1A1FFAR1 | |
| SCHEMBL1673387 | 0.85 | NPSR1 (0.47) | NPSR1CNR2GPR88ALDH1A1AOC3 | |
| SCHEMBL517086 | 0.84 | RIPK1 (0.41) | LMNAMAPTTP53 | |
| SCHEMBL836812 | 0.81 | NPSR1 (0.48) | NPSR1CNR2GPR88ALDH1A1AOC3 | |
| SCHEMBL16164204 | 0.81 | NPSR1 (0.49) | NPSR1CNR2GPR88ALDH1A1AOC3 | |
| SCHEMBL1443078 | 0.79 | KMT2A (0.47) | NPSR1CNR2GPR88ALDH1A1L3MBTL1 | |
| SCHEMBL15674962 | 0.76 | CNR2 (0.41) | NPSR1CNR2GPR88ALDH1A1L3MBTL1 | |
| SCHEMBL1442862 | 0.75 | GPR88 (0.48) | NPSR1CNR2GPR88ALDH1A1TP53 | |
| SCHEMBL17935535 | 0.74 | ABCB1 (0.48) | NPSR1CNR2GPR88ALDH1A1SLC2A1 | |
| SCHEMBL15101521 | 0.71 | ALDH1A1 (0.50) | CNR2ALDH1A1SMN1; SMN2LDHAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092501-A1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092501-A1 | NOVEL INHIBITORS | GLUL, QPCT, GLS | NPSR1 3094/4885CNR2 2749/4885GPR88 1678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.