SCHEMBL16738656

SCHEMBL16738656

CC(C)(C(=O)O)C(=O)OCc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.61
PPARG P37231 5/20 0.56
ALDH1A1 P00352 6/20 0.55
HTT P42858 4/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
ATM Q13315 1/20 0.51
NPSR1 Q6W5P4 3/20 0.51
CYP2C9 P11712 3/20 0.51
CYP2C19 P33261 3/20 0.51
HPGD P15428 2/20 0.51
MAPT P10636 2/20 0.51
PPARA Q07869 3/20 0.49
RAB9A P51151 2/20 0.49
GAA P10253 1/20 0.49
LMNA P02545 1/20 0.48
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991532 0.87 ALDH1A1 (0.58) ELANEALDH1A1SMN1; SMN2L3MBTL1HPGD
SCHEMBL16738659 0.82 ALDH1A1 (0.52) ELANEPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL991531 0.80 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2L3MBTL1HPGDMAPT
SCHEMBL19872027 0.78 ALDH1A1 (0.50) ALDH1A1HTTSMN1; SMN2ATMRAB9A
SCHEMBL18213792 0.78 PPARG (0.57) ELANEPPARGALDH1A1HTTSMN1; SMN2
SCHEMBL28580976 0.77 KMT2A (0.79) ALDH1A1HTTSMN1; SMN2L3MBTL1ATM
SCHEMBL10483707 0.76 ELANE (1.00) ELANEPPARGL3MBTL1MAPTPPARA
SCHEMBL5395231 0.76 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2L3MBTL1HPGDMAPT
SCHEMBL11883903 0.76 LMNA (0.60) PPARGALDH1A1HTTSMN1; SMN2L3MBTL1
SCHEMBL11472200 0.75 ATM (0.66) ELANEPPARGALDH1A1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150148441-A1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST A/S (DK) 2015-05-28 US claimed
US-20150148441-A1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS COLOPLAST A/S (DK) 2015-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148441-A1 NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS PPOX, ALAD, AAAS ELANE 2285/4885PPARG 2358/4885ALDH1A1 366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.