Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16740602 | 0.69 | PRKCZ (1.00) | PRKCZMEN1KMT2AMAOAMAOB | |
| SCHEMBL16740583 | 0.60 | PRKCZ (1.00) | PRKCZMEN1KMT2AMAOAMAOB | |
| SCHEMBL28801722 | 0.55 | ALOX5 (0.44) | MEN1KMT2AHTR6TP53HTR3E | |
| SCHEMBL18177888 | 0.54 | DRD2 (0.65) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL10349573 | 0.54 | PRKCZ (0.48) | PRKCZALDH1A1MAOAMAOBHTR6 | |
| SCHEMBL14680371 | 0.53 | ALDH1A1 (1.00) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL1133351 | 0.53 | ALOX5 (0.52) | ALDH1A1MEN1MAPTKMT2AHTR6 | |
| SCHEMBL10948802 | 0.53 | MEN1 (0.49) | ALDH1A1LMNAMEN1MAPTKMT2A | |
| SCHEMBL11100857 | 0.52 | ALDH1A1 (0.75) | ALDH1A1LMNAMAPTALOX12HTR6 | |
| Parachlorophenol SCHEMBL7749035 | 0.52 | TSHR (0.81) | ALDH1A1LMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015075051-A1 | ALLOSTERIC INHIBITORS OF ATYPICAL PROTEIN KINASES C | UNIVERSITAET DES SAARLANDES (DE) | 2015-05-28 | — | — | WO | disclosed |